iPTMnet Report for Q68CQ4 (UTP25)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q68CQ4 / UTP25_HUMAN
Protein Name U3 small nucleolar RNA-associated protein 25 homolog
Gene Name Name: UTP25
Synonyms:C1orf107,DEF;
Organism Homo sapiens (Human)

PRO ID PR:Q68CQ4
DAG View
PRO Name U3 small nucleolar RNA-associated protein 25 homolog (human)
Definition A digestive organ expansion factor that is encoded in the genome of human.
Short Label hUTP25
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q68CQ4 (UTP25) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation HPRD   PhosphoSitePlus 18212344
S10 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 18212344
T15 Phosphorylation PhosphoSitePlus
T17 Phosphorylation PhosphoSitePlus
R25 Methylation PhosphoSitePlus
Y34 Phosphorylation PhosphoSitePlus
R36 Methylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
S50 Phosphorylation RLIMS-P   UniProt 27657329
S58 Phosphorylation RLIMS-P   UniProt 27657329
S62 Phosphorylation RLIMS-P   UniProt 27657329
S150 Phosphorylation PhosphoSitePlus
S153 Phosphorylation HPRD   PhosphoSitePlus 19413330
S186 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
S398 Phosphorylation HPRD   PhosphoSitePlus 18452278
S451 Phosphorylation PhosphoSitePlus
Y688 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S38 F38 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S58 F58 Biomuta DOID:1612 / breast cancer [ cosmic ]
S150 P150 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S150 A150 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S186 F186 Biomuta DOID:363 / uterine cancer [ icgc ]
S273 I273 Biomuta DOID:1324 / lung cancer [ cosmic ]
S451 Y451 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]