iPTMnet Report for Q68CJ9 (CREB3L3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q68CJ9 / CR3L3_HUMAN
Protein Name Cyclic AMP-responsive element-binding protein 3-like protein 3
Gene Name Name: CREB3L3
Synonyms:CREBH;ORFNames:HYST1481;
Organism Homo sapiens (Human)

PRO ID PR:Q68CJ9
DAG View
PRO Name cyclic AMP-responsive element-binding protein 3-like protein 3 (human)
Definition A cyclic AMP-responsive element-binding protein 3-like protein 3 that is encoded in the genome of human.
Short Label hCREB3L3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q68CJ9 (CREB3L3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S73 Phosphorylation RLIMS-P 28381424
S81 Phosphorylation RLIMS-P 28381424
S87 Phosphorylation RLIMS-P 28381424
S173 Phosphorylation PhosphoSitePlus   UniProt 24275569
K225 Ubiquitination PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
Y267 Phosphorylation PhosphoSitePlus
T273 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
K294 Acetylation PhosphoSitePlus
K294 Ubiquitination UniProt 30389664
T347 O-Glycosylation GlyGen 30459171
S360 Phosphorylation PhosphoSitePlus
S379 O-Glycosylation GlyGen   UniProt 22171320
S395 Phosphorylation PhosphoSitePlus
N413 N-Glycosylation GlyGen   UniProt 20356926
N420 N-Glycosylation GlyGen   UniProt 20356926
N427 N-Glycosylation GlyGen   UniProt 20356926
T429 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S256 Phosphorylation HPRD 17924679
S260 Phosphorylation HPRD 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S87 G87 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T229 P229 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T229 I229 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T229 A229 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S256 L256 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S260 R260 Biomuta DOID:1324 / lung cancer [ cosmic ]
S276 P276 Biomuta DOID:1324 / lung cancer [ cosmic ]
T347 S347 Biomuta DOID:4159 / skin cancer [ cosmic ]
S360 F360 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ]
S395 F395 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]