iPTMnet Report for Q676U5 (ATG16L1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q676U5 / A16L1_HUMAN
Protein Name Autophagy-related protein 16-1
Gene Name Name: ATG16L1
Synonyms:APG16L;ORFNames:UNQ9393/PRO34307;
Organism Homo sapiens (Human)

PRO ID PR:Q676U5
DAG View
PRO Name autophagy-related protein 16-1 (human)
Definition An autophagy-related protein 16-1 that is encoded in the genome of human.
Short Label hATG16L1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q676U5 (ATG16L1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus   UniProt 26083323
K151 Methylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
T247 Phosphorylation phospho.ELM 18669648
T254 Phosphorylation phospho.ELM 18669648
S255 Phosphorylation PhosphoSitePlus
T265 Phosphorylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus   UniProt 20068231
S278 Phosphorylation PhosphoSitePlus   RLIMS-P 32168879
S287 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S289 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S290 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T300 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S70 Phosphorylation HPRD 20068231
T247 Phosphorylation HPRD 18669648
T254 Phosphorylation HPRD 18669648
S269 Phosphorylation HPRD 18077418, 20068231
S287 Phosphorylation HPRD 19651622, 18669648, 20068231, ...17924679
S289 Phosphorylation HPRD 18669648, 20068231
S290 Phosphorylation HPRD 18669648, 20068231, 17924679
S304 Phosphorylation HPRD 20068231, 17924679
Site PTM Type PTM Enzyme Score Source PMID
S70 Phosphorylation HPRD 20068231
T247 Phosphorylation HPRD 18669648
T254 Phosphorylation HPRD 18669648
T265 Phosphorylation PhosphoSitePlus
S268 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648, 20068231, ...17924679
S270 Phosphorylation HPRD 18669648, 20068231
S271 Phosphorylation HPRD 18669648, 20068231, 17924679
S285 Phosphorylation HPRD 20068231, 17924679
Site PTM Type PTM Enzyme Score Source PMID
S269 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S70 I70 Biomuta DOID:363 / uterine cancer [ icgc ]
S271 F271 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]