iPTMnet Report for Q66K14 (TBC1D9B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q66K14 / TBC9B_HUMAN
Protein Name TBC1 domain family member 9B
Gene Name Name: TBC1D9B
Synonyms:KIAA0676;
Organism Homo sapiens (Human)

PRO ID PR:Q66K14
DAG View
PRO Name TBC1 domain family member 9B (human)
Definition A TBC1 domain family member 9B that is encoded in the genome of human.
Short Label hTBC1D9B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q66K14 (TBC1D9B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R34 Methylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K146 Acetylation PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
T374 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
K396 Acetylation PhosphoSitePlus
T397 Phosphorylation PhosphoSitePlus   UniProt 23186163
K400 Acetylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
S411 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 19690332, ...24275569
S416 Phosphorylation PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
S420 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S427 Phosphorylation PhosphoSitePlus
S432 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 19690332, ...20068231
S435 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19369195, ...15302935, 18669648, 19690332
S439 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
T450 O-Glycosylation GlyGen 35132862
S463 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S512 Phosphorylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
Y693 Phosphorylation IEDB 35494241
S752 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus
K802 Ubiquitination PhosphoSitePlus
Y824 Phosphorylation PhosphoSitePlus
S834 Phosphorylation PhosphoSitePlus
Y836 Phosphorylation PhosphoSitePlus
S850 Phosphorylation PhosphoSitePlus
Y853 Phosphorylation PhosphoSitePlus
Y857 Phosphorylation PhosphoSitePlus
S897 Phosphorylation PhosphoSitePlus
Y912 Phosphorylation PhosphoSitePlus
T917 Phosphorylation PhosphoSitePlus
S994 Phosphorylation PhosphoSitePlus
S995 Phosphorylation PhosphoSitePlus
Y998 Phosphorylation PhosphoSitePlus
C1079 S-Nitrosylation dbSNO 26338901
S1138 Phosphorylation PhosphoSitePlus
S1144 Phosphorylation PhosphoSitePlus
T1209 Phosphorylation PhosphoSitePlus
S1211 Phosphorylation PhosphoSitePlus
S1238 Phosphorylation PhosphoSitePlus
T1239 Phosphorylation PhosphoSitePlus
S1241 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1249 O-Glycosylation GlyGen 30620550
S1249 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S399 Phosphorylation HPRD 18767875, 20068231
S404 Phosphorylation HPRD 20068231
S411 Phosphorylation HPRD 18669648, 20068231
S420 Phosphorylation HPRD 18691976, 18669648, 20068231
S432 Phosphorylation HPRD 19413330, 18691976, 18669648, ...20068231
S435 Phosphorylation HPRD 19413330, 18691976, 18669648, ...20068231
S463 Phosphorylation HPRD 18691976, 18669648, 20068231
S1138 Phosphorylation HPRD 18691976
S1144 Phosphorylation HPRD 18691976
S1238 Phosphorylation HPRD 20068231
T1239 Phosphorylation HPRD 20068231
S1241 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S399 Phosphorylation HPRD 18767875, 20068231
S404 Phosphorylation HPRD 20068231
S411 Phosphorylation HPRD   PhosphoSitePlus 18669648, 20068231
S420 Phosphorylation HPRD 18691976, 18669648, 20068231
S432 Phosphorylation HPRD 19413330, 18691976, 18669648, ...20068231
S435 Phosphorylation HPRD 19413330, 18691976, 18669648, ...20068231
S463 Phosphorylation HPRD 18691976, 18669648, 20068231
Y946 Phosphorylation PhosphoSitePlus
S1121 Phosphorylation HPRD 18691976
S1127 Phosphorylation HPRD 18691976
S1221 Phosphorylation HPRD   PhosphoSitePlus 20068231
T1222 Phosphorylation HPRD 20068231
S1224 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K262 N262 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S275 L275 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S275 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K278 N278 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S363 C363 Biomuta DOID:4159 / skin cancer [ cosmic ]
S420 F420 Biomuta DOID:4159 / skin cancer [ cosmic ]
S427 L427 Biomuta DOID:5041 / esophageal cancer [ tcga ]
T450 A450 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
Y946 C946 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1121 L1121 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S1138 L1138 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1211 T1211 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S1211 F1211 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]