iPTMnet Report for Q66GS9 (CEP135)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q66GS9 / CP135_HUMAN
Protein Name Centrosomal protein of 135 kDa
Gene Name Name: CEP135
Synonyms:CEP4,KIAA0635;
Organism Homo sapiens (Human)

PRO ID PR:Q66GS9
DAG View
PRO Name centrosomal protein of 135 kDa (human)
Definition A centrosomal protein of 135 kDa that is encoded in the genome of human.
Short Label hCEP135
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q66GS9 (CEP135) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K51 Acetylation PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
T156 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
S261 O-Glycosylation GlyGen 30379171
S261 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
K354 Acetylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus   UniProt 23186163
K389 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus   UniProt 23186163
S441 Phosphorylation PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
T488 Phosphorylation PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
T502 Phosphorylation PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
Y518 Phosphorylation PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
S548 Phosphorylation PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
T555 Phosphorylation PhosphoSitePlus
T557 O-Glycosylation GlyGen 30379171
T557 Phosphorylation PhosphoSitePlus
T558 O-Glycosylation GlyGen 30379171
K569 Ubiquitination PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
K585 Ubiquitination PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
K603 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K635 Ubiquitination PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
K663 Ubiquitination PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus   UniProt 23186163
K702 Ubiquitination PhosphoSitePlus
K727 Acetylation PhosphoSitePlus
K727 Ubiquitination PhosphoSitePlus
T728 Phosphorylation PhosphoSitePlus
K734 Ubiquitination PhosphoSitePlus
K749 Ubiquitination PhosphoSitePlus
T784 Phosphorylation PhosphoSitePlus
K804 Ubiquitination PhosphoSitePlus
K818 Methylation PhosphoSitePlus
K818 Ubiquitination PhosphoSitePlus
K857 Ubiquitination PhosphoSitePlus
K874 Ubiquitination PhosphoSitePlus
K951 Ubiquitination PhosphoSitePlus
K967 Ubiquitination PhosphoSitePlus
S976 Phosphorylation PhosphoSitePlus
K983 Ubiquitination PhosphoSitePlus
K988 Ubiquitination PhosphoSitePlus
S1014 Phosphorylation PhosphoSitePlus
S1016 Phosphorylation PhosphoSitePlus
K1031 Ubiquitination PhosphoSitePlus
K1043 Ubiquitination PhosphoSitePlus
K1085 Ubiquitination PhosphoSitePlus
K1097 Ubiquitination PhosphoSitePlus
T1121 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1126 Phosphorylation PhosphoSitePlus
S1130 Phosphorylation PhosphoSitePlus
S1132 Phosphorylation PhosphoSitePlus
S1134 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S253 Phosphorylation HPRD 19691289
S439 Phosphorylation HPRD 19651622, 17081983
Y518 Phosphorylation HPRD 19664994
T1121 Phosphorylation HPRD 17081983
S1126 Phosphorylation HPRD 17081983
T1127 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K148 N148 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S261 F261 Biomuta DOID:4362 / cervical cancer [ icgc ]
K403 T403 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T488 A488 Biomuta DOID:3571 / liver cancer [ cosmic ]
T728 I728 Biomuta DOID:4159 / skin cancer [ cosmic ]
K749 N749 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K749 E749 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S976 F976 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1031 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1126 F1126 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1130 C1130 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1130 F1130 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1134 Y1134 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]