Protein Information

Cytoscape View


UniProt AC / UniProt ID Q64511 / TOP2B_MOUSE
Protein Name DNA topoisomerase 2-beta
Gene Name Name: Top2b
Organism Mus musculus (Mouse)

PRO ID PR:Q64511
DAG View
PRO Name DNA topoisomerase 2-beta (mouse)
Definition A DNA topoisomerase 2-beta that is encoded in the genome of mouse.
Short Label mTOP2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q64511 (Top2b) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 23806337
K3 Acetylation UniProt 23806337
T14 Phosphorylation PhosphoSitePlus
T20 Phosphorylation PhosphoSitePlus
C414 S-Nitrosylation dbSNO 20925432
S419 Phosphorylation phospho.ELM   PhosphoSitePlus 17203969
T627 Phosphorylation phospho.ELM   PhosphoSitePlus 17203969
S764 Phosphorylation PhosphoSitePlus
Y766 Phosphorylation PhosphoSitePlus
T776 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus
S1224 Phosphorylation PhosphoSitePlus
Y1226 Phosphorylation PhosphoSitePlus
T1278 Phosphorylation PhosphoSitePlus
K1304 Acetylation PhosphoSitePlus
K1315 Acetylation PhosphoSitePlus
K1316 Acetylation PhosphoSitePlus
S1324 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1328 Phosphorylation PhosphoSitePlus
S1330 Phosphorylation PhosphoSitePlus
S1332 Phosphorylation PhosphoSitePlus
Y1358 Phosphorylation PhosphoSitePlus   UniProt 21183079
T1359 Phosphorylation PhosphoSitePlus
S1363 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1376 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1387 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17242355, 17203969, 21183079
T1390 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1400 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19144319, 21183079, 17203969
Y1408 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1412 Phosphorylation PhosphoSitePlus
S1428 Phosphorylation PhosphoSitePlus
S1439 Phosphorylation PhosphoSitePlus
S1444 Phosphorylation PhosphoSitePlus
S1448 Phosphorylation PhosphoSitePlus
S1453 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21183079, 17203969, 17242355
T1458 Phosphorylation phospho.ELM   PhosphoSitePlus 17203969
S1460 Phosphorylation PhosphoSitePlus   UniProt 21183079
T1506 Phosphorylation PhosphoSitePlus
S1509 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19144319, 17242355, 19131326, ...21183079
S1511 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19144319, 17242355, 19131326, ...21183079
S1513 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17242355, 21183079
K1535 Acetylation PhosphoSitePlus
S1537 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17242355, 21183079
S1539 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17242355, 21183079
K1553 Acetylation PhosphoSitePlus
K1557 Acetylation PhosphoSitePlus
K1558 Acetylation PhosphoSitePlus
T1562 Phosphorylation PhosphoSitePlus
S1563 Phosphorylation PhosphoSitePlus
S1568 Phosphorylation PhosphoSitePlus   UniProt 21183079
S1575 Phosphorylation PhosphoSitePlus
S1600 Phosphorylation PhosphoSitePlus