iPTMnet Report for Q641Q2 (WASHC2A)
Protein Information
| UniProt AC / UniProt ID | Q641Q2 / WAC2A_HUMAN |
| Protein Name | WASH complex subunit 2A |
| Gene Name | Name: WASHC2A Synonyms:FAM21A; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q641Q2 |
| PRO Name | WASH complex subunit 2A (human) |
| Definition | A WASH complex subunit 2A that is encoded in the genome of human. |
| Short Label | hWASHC2A |
| Category | organism-gene |
Q641Q2 (WASHC2A) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T6 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S31 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 33936100 | ||
| S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K110 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y179 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S210 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S213 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S217 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S230 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S265 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S284 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T287 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S288 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 27920218 | ||
| T311 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S314 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T331 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S333 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T347 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S352 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S356 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S362 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S375 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R385 | Methylation | score1 | PhosphoSitePlus | |||
| S390 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S395 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S396 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S397 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S398 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K402 | Acetylation | score1 | PhosphoSitePlus | |||
| S410 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T416 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S423 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y443 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T448 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S478 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S498 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T502 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S504 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T506 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K523 | Acetylation | score1 | PhosphoSitePlus | |||
| S529 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S539 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 18669648, ... | ||
| S544 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S550 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S552 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S571 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K590 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T592 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S619 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S620 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S648 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T650 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S653 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S663 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S680 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S700 | Phosphorylation | score1 | PhosphoSitePlus | 21659604 | ||
| S700 | Phosphorylation | P42345 (MTOR) | score1 | PhosphoSitePlus | 21659604 | |
| S704 | Phosphorylation | score1 | PhosphoSitePlus | 21659604 | ||
| S704 | Phosphorylation | P42345 (MTOR) | score1 | PhosphoSitePlus | 21659604 | |
| T718 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S728 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S741 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S748 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S752 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K754 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T758 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S763 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K765 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S772 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S784 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S785 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S786 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S787 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T793 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K798 | Acetylation | score1 | PhosphoSitePlus | |||
| T799 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S802 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S836 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K850 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K869 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S877 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S893 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S909 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S912 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S925 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T935 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S991 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S996 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1008 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1026 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1053 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1054 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S1075 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1087 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 19690332 | ||
| T1092 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1114 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 19690332, 20068231 | ||
| S1119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1123 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1142 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1169 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1179 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1180 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1195 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1289 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1309 | Acetylation | score1 | PhosphoSitePlus | |||
| K1311 | Acetylation | score1 | PhosphoSitePlus | |||
| S1328 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S158 | Phosphorylation | score0 | HPRD | 19413330, 20068231 | ||
| S160 | Phosphorylation | score0 | HPRD | 19413330, 20068231 | ||
| Y179 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S230 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
| S238 | Phosphorylation | score0 | HPRD | 19651622, 20068231, 18452278 | ||
| S284 | Phosphorylation | score0 | HPRD | 19651622, 20068231, 18452278 | ||
| T287 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
| S288 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
| S314 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T331 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S333 | Phosphorylation | score0 | HPRD | 19651622, 20068231, 18452278 | ||
| S352 | Phosphorylation | score0 | HPRD | 19413330, 18767875, 20068231 | ||
| S478 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
| S498 | Phosphorylation | score0 | HPRD | 19413330, 16964243, 20058876, ... | ||
| T502 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T506 | Phosphorylation | score0 | HPRD | 19413330 | ||
| S520 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S528 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S529 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S539 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 19664994, ... | ||
| S614 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S619 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S620 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S653 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S680 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S697 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S704 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S728 | Phosphorylation | score0 | HPRD | 19413330, 18767875, 20068231 | ||
| S784 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S786 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S787 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S802 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 20068231 | ||
| S909 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T935 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S996 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1001 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1053 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1054 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1075 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1114 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1144 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1169 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1179 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1180 | Phosphorylation | score0 | HPRD | 19413330, 20058876, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K63 | T63 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K110 | T110 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S520 | P520 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S528 | P528 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S529 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S552 | G552 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| S1053 | F1053 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S1180 | N1180 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S1289 | Y1289 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View