iPTMnet Report for Q63HQ0 (AP1AR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q63HQ0 / AP1AR_HUMAN
Protein Name AP-1 complex-associated regulatory protein
Gene Name Name: AP1AR
Synonyms:C4orf16;ORFNames:PRO0971;
Organism Homo sapiens (Human)

PRO ID PR:Q63HQ0
DAG View
PRO Name AP-1 complex-associated regulatory protein (human)
Definition An AP-1 complex-associated regulatory protein that is encoded in the genome of human.
Short Label hAP1AR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q63HQ0 (AP1AR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S29 Phosphorylation PhosphoSitePlus   UniProt 23186163
K30 Ubiquitination PhosphoSitePlus
Y77 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
T178 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
T194 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus   UniProt 23186163
T228 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Site PTM Type PTM Enzyme Score Source PMID
Y145 Phosphorylation HPRD 19901323
Y165 Phosphorylation HPRD 15144186
S226 Phosphorylation HPRD 18578522
T228 Phosphorylation HPRD 20166139, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y110 H110 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y137 C137 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y165 C165 Biomuta DOID:184 / bone cancer [ cosmic ]
S174 L174 Biomuta DOID:4159 / skin cancer [ cosmic ]
S174 A174 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T178 A178 Biomuta DOID:363 / uterine cancer [ cosmic ]
S205 F205 Biomuta DOID:4159 / skin cancer [ cosmic ]