iPTMnet Report for Q63932 (Map2k2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q63932 / MP2K2_MOUSE
Protein Name Dual specificity mitogen-activated protein kinase kinase 2
Gene Name Name: Map2k2
Synonyms:Mek2,Mkk2,Prkmk2;
Organism Mus musculus (Mouse)

PRO ID PR:Q63932
DAG View
PRO Name dual specificity mitogen-activated protein kinase kinase 2 (mouse)
Definition A dual specificity mitogen-activated protein kinase kinase 2 that is encoded in the genome of mouse.
Short Label mMAP2K2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q63932 (Map2k2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
T25 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S222 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15665076, 12604616, 10409742
S226 Phosphorylation phospho.ELM   PhosphoSitePlus 15665076, 12604616
S235 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus   RLIMS-P 28225038
K362 Ubiquitination PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus
T397 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q63932 (Map2k2) S306 P31750 (Akt1) unknown eFIP 28225038