Protein Information

Cytoscape View


UniProt AC / UniProt ID Q63844 / MK03_MOUSE
Protein Name Mitogen-activated protein kinase 3
Gene Name Name: Mapk3
Synonyms:Erk1,Prkm3;
Organism Mus musculus (Mouse)

PRO ID PR:Q63844
DAG View
PRO Name mitogen-activated protein kinase 3 (mouse)
Definition A mitogen-activated protein kinase 3 that is encoded in the genome of mouse.
Short Label mMAPK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q63844 (Mapk3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y61 Phosphorylation PhosphoSitePlus
T128 Phosphorylation PhosphoSitePlus
Y131 Phosphorylation PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
T203 Phosphorylation P31938 (Map2k1) phospho.ELM   PhosphoSitePlus   UniProt 17947660, 1518847, 21183079, ...19131326, 18034455, 16186792, 12167697
Y205 Phosphorylation P31938 (Map2k1) phospho.ELM   PhosphoSitePlus   UniProt 17947660, 12032835, 21183079, ...19131326, 18034455, 16186792, 12167697
T208 Phosphorylation PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus
S220 Phosphorylation RLIMS-P 28986096
K221 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T203 Phosphorylation PRO 11841548, 11726647, 11684667, ...15314156, 15383658
Y205 Phosphorylation PRO 11841548, 11726647, 15383658, ...15314156, 11684667


Q63844 (Mapk3) as PTM Enzyme



Substrate Site Score Source PMID
O08537 (Esr2) S87 PhosphoSitePlus 10230404
O08537 (Esr2) S105 PhosphoSitePlus 10230404
O54918 (Bcl2l11) S55 PhosphoSitePlus 15486085
O54918 (Bcl2l11) S65 PhosphoSitePlus 17105963, 15486085
O54918 (Bcl2l11) S100 PhosphoSitePlus 15486085
O54918 (Bcl2l11) T112 PhosphoSitePlus 18498746
P05627 (Jun) S63 PhosphoSitePlus 12881422
P05627 (Jun) S73 PhosphoSitePlus 12881422
P09450 (Junb) S256 PhosphoSitePlus 23712012
P10417 (Bcl2) S70 PhosphoSitePlus 10677502
P15037 (Ets2) T72 phospho.ELM   PhosphoSitePlus 9710599
P15806 (Tcf3) T353 Signor 14592976
P16951 (Atf2) T53 PhosphoSitePlus 16601071
P17679 (Gata1) S26 PhosphoSitePlus 15967790
P18653 (Rps6ka1) S369 PhosphoSitePlus 22698694
P18654 (Rps6ka3) S386 PhosphoSitePlus 10480933
P20444 (Prkca) T638 PhosphoSitePlus 20513439
P22091 (Tal1) S122 PhosphoSitePlus 10527940
P24529 (Th) S31 PhosphoSitePlus 15447670
P28033 (Cebpb) T188 phospho.ELM   PhosphoSitePlus 15367685, 17601773, 17264204, ...18339625
P31750 (Akt1) T308 PhosphoSitePlus 12388598
P31938 (Map2k1) T286 RLIMS-P+ 25971971
P31938 (Map2k1) T292 PhosphoSitePlus 8013650
P31938 (Map2k1) T386 PhosphoSitePlus 8013650
P33242 (Nr5a1) S203 PhosphoSitePlus 12242296
P34152-3 (Ptk2) S910 PhosphoSitePlus 15174091
P35569 (Irs1) S612 PhosphoSitePlus   Signor 9395471, 14579029
P35569 (Irs1) S632 Signor 14579029
P35569 (Irs1) S731 Signor 14579029
P41969 (Elk1) S325 PhosphoSitePlus 7889942
P41969 (Elk1) T337 PhosphoSitePlus 7889942
P41969 (Elk1) S384 phospho.ELM   PhosphoSitePlus 18086672, 18160653, 7889942
P41969 (Elk1) S390 phospho.ELM   PhosphoSitePlus 7889942
P41969 (Elk1) S423 PhosphoSitePlus 7889942
P42225 (Stat1) S727 PhosphoSitePlus 18378670
P47713 (Pla2g4a) S505 phospho.ELM   PhosphoSitePlus 8381049
P49138 (Mapkapk2) T208 phospho.ELM   PhosphoSitePlus 7592979
P49138 (Mapkapk2) T320 phospho.ELM   PhosphoSitePlus 7592979
P51557 (Star) S232 PhosphoSitePlus 19007846
P54227 (Stmn1) S25 PhosphoSitePlus 22698694, 19688729
P70671 (Irf3) S171 PhosphoSitePlus 23892079
P98083 (Shc1) S36 PhosphoSitePlus 15930121
Q00175 (Pgr) S294 phospho.ELM   PhosphoSitePlus 12529413
Q61037 (Tsc2) S540 Signor 15851026
Q61037 (Tsc2) S664 Signor 15851026
Q640N1 (Aebp1) T1003 PhosphoSitePlus 15654748
Q8CJ00 (Noxa1) Y252 PhosphoSitePlus 20230789
Q8K120 (Nfatc4) S676 PhosphoSitePlus 18086672
Q8K4Q0 (Rptor) S863 Signor 21757713
Q8VI36 (Pxn) S83 PhosphoSitePlus 15494312
Q8VI36 (Pxn) S130 PhosphoSitePlus 16537926
Q9CT10 (Ranbp3) S58 PhosphoSitePlus 20026644
Q9ERR1 (Ndel1) T219 PhosphoSitePlus 18331715
Q9ERT9 (Ppp1r1a) S67 PhosphoSitePlus 11278334
Q9JHG6 (Rcan1) S112 PhosphoSitePlus   Signor 12063245
Q9Z0F8 (Adam17) T735 PhosphoSitePlus 15923650
Q9Z0V2 (Kcnd2) S616 PhosphoSitePlus 16600858, 18045912


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036468 (mMAPK3/iso:1/Phos:1) pT203,pY205 PRO 11684667, 11726647, 11841548, ...15314156, 15383658


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:Q63844-1 (mMAPK3/iso:1) Interaction PR:Q9DAJ4 (mWDR83) PRO 15118098