iPTMnet Report Q62406 Irak1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q62406 / IRAK1_MOUSE
Protein Name	Interleukin-1 receptor-associated kinase 1
Gene Name	Name: Irak1 Synonyms:Il1rak;
Organism	Mus musculus (Mouse)

PRO ID	PR:Q62406 DAG View
PRO Name	interleukin-1 receptor-associated kinase 1 (mouse)
Definition	An interleukin-1 receptor-associated kinase 1 that is encoded in the genome of mouse.
Short Label	mIRAK1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q62406 (Irak1) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T66	Phosphorylation		score1	PhosphoSitePlus
	S131	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	21743479
	K134	Ubiquitination		score1	PhosphoSitePlus
	S144	Phosphorylation		score0	RLIMS-P	21743479
	S173	Phosphorylation		score0	RLIMS-P	21743479
	S185	Phosphorylation		score1	PhosphoSitePlus
	K371	Ubiquitination		score1	PhosphoSitePlus
	T387	Phosphorylation		score0	RLIMS-P	26512959

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T209	Phosphorylation		score2	PRO	12538665

Q62406 (Irak1) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	P35569 (Irs1)	S24	score2	RLIMS-P+	15849359
	P42227 (Stat3)	S727	score2	PhosphoSitePlus	15465816
	Q9ESJ7 (Irak1bp1)	S55	score2	PhosphoSitePlus	17079333
	Q9ESJ7 (Irak1bp1)	S61	score2	PhosphoSitePlus	17079333
	Q9ESJ7 (Irak1bp1)	S63	score2	PhosphoSitePlus	17079333
	Q9ESJ7 (Irak1bp1)	S234	score2	PhosphoSitePlus	17079333
	Q9ESJ7 (Irak1bp1)	T236	score2	PhosphoSitePlus	17079333
	Q9ESJ7 (Irak1bp1)	S241	score2	PhosphoSitePlus	17079333
	Q9ESJ7 (Irak1bp1)	T246	score2	PhosphoSitePlus	17079333

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000027178 (mIRAK1/iso:1/Phos:1)	pT209		PRO	12538665