Protein Information

Cytoscape View


UniProt AC / UniProt ID Q61214 / DYR1A_MOUSE
Protein Name Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Gene Name Name: Dyrk1a
Synonyms:Dyrk;
Organism Mus musculus (Mouse)

PRO ID PR:Q61214
DAG View
PRO Name dual specificity tyrosine-phosphorylation-regulated kinase 1A (mouse)
Definition A dual specificity tyrosine-phosphorylation-regulated kinase 1A that is encoded in the genome of mouse.
Short Label mDYRK1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q61214 (Dyrk1a) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus   UniProt 18034455
Y147 Phosphorylation PhosphoSitePlus
Y319 Phosphorylation PhosphoSitePlus
Y321 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455, 12522270
S324 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
T466 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
S538 Phosphorylation PhosphoSitePlus   UniProt 21183079
S748 Phosphorylation PhosphoSitePlus   UniProt 21183079
S758 Phosphorylation PhosphoSitePlus   UniProt 21183079


Q61214 (Dyrk1a) as PTM Enzyme



Substrate Site Score Source PMID
O08599 (Stxbp1) T479 RLIMS-P+ 22765017
P35436 (Grin2a) S1048 RLIMS-P+ 25368549
P46414 (Cdkn1b) S10 RLIMS-P+ 24806449
Q8C3Q9 (Casp9) T163 PhosphoSitePlus 19081073
Q9R194 (Cry2) S557 PhosphoSitePlus 20123978