iPTMnet Report for Q60795 (Nfe2l2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q60795 / NF2L2_MOUSE
Protein Name Nuclear factor erythroid 2-related factor 2
Gene Name Name: Nfe2l2
Synonyms:Nrf2;
Organism Mus musculus (Mouse)

PRO ID PR:Q60795
DAG View
PRO Name nuclear factor erythroid 2-related factor 2 (mouse)
Definition A nuclear factor erythroid 2-related factor 2 that is encoded in the genome of mouse.
Short Label mNFE2L2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q60795 (Nfe2l2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 32602850, 30685263, 33136552, ...33466349, 32210977, 25582778, 28373747, 30282635, 26845617, 34092244, 28257879, 33671212, 32259797, 31281590, 12947090, 32630085, 29353218, 24967692, 33241629, 33532181, 27151674
S40 Phosphorylation P20444 (Prkca) PhosphoSitePlus 12947090
S335 Phosphorylation PhosphoSitePlus   RLIMS-P 31945188, 21245377
S335 Phosphorylation Q9WV60 (Gsk3b) PhosphoSitePlus 21245377
S338 Phosphorylation PhosphoSitePlus 21245377
S338 Phosphorylation Q9WV60 (Gsk3b) PhosphoSitePlus 21245377
S342 Phosphorylation PhosphoSitePlus 21245377
S342 Phosphorylation Q9WV60 (Gsk3b) PhosphoSitePlus 21245377
S347 Phosphorylation PhosphoSitePlus 21245377
S347 Phosphorylation Q9WV60 (Gsk3b) PhosphoSitePlus 21245377
S351 Phosphorylation PhosphoSitePlus   RLIMS-P 33875681, 21245377
S351 Phosphorylation Q9WV60 (Gsk3b) PhosphoSitePlus 21245377
S355 Phosphorylation PhosphoSitePlus 21245377
S355 Phosphorylation Q9WV60 (Gsk3b) PhosphoSitePlus 21245377
S365 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus   RLIMS-P 27161318
S558 Phosphorylation RLIMS-P 27161318
Y568 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 33532181, 23661004, 16513647
Y568 Phosphorylation P39688 (Fyn) PhosphoSitePlus 16513647


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q60795 (Nfe2l2) S40 Q9Z2X8 (Keap1) unknown eFIP 32079324
Phosphorylation Q60795 (Nfe2l2) S40 Q14145 (KEAP1) increased_association eFIP 32938017