iPTMnet Report Q60680 Chuk

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q60680 / IKKA_MOUSE
Protein Name	Inhibitor of nuclear factor kappa-B kinase subunit alpha
Gene Name	Name: Chuk Synonyms:Ikka;
Organism	Mus musculus (Mouse)

PRO ID	PR:Q60680 DAG View
PRO Name	inhibitor of nuclear factor kappa-B kinase subunit alpha (mouse)
Definition	An inhibitor of nuclear factor kappa-B kinase subunit alpha that is encoded in the genome of mouse.
Short Label	mCHUK
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q60680 (Chuk) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T23	Phosphorylation		score1	PhosphoSitePlus
	S176	Phosphorylation		score1	PhosphoSitePlus
	S180	Phosphorylation		score1	PhosphoSitePlus
	T499	Phosphorylation		score1	PhosphoSitePlus
	K506	Ubiquitination		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S176	Phosphorylation		score2	PRO	16751795
	S180	Phosphorylation		score2	PRO	16751795

Q60680 (Chuk) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	P25799 (Nfkb1)	S926	score1	Signor	11297557
	P25799 (Nfkb1)	S930	score1	Signor	11297557
	P25799 (Nfkb1)	S935	score1	Signor	11297557
	P35569 (Irs1)	S307	score2	PhosphoSitePlus	15143153
	Q04207 (Rela)	S534	score3	PhosphoSitePlus	15858576, 16135789
	Q3UKC1 (Tax1bp1)	S693	score1	Signor	21765415
	Q9WTK5 (Nfkb2)	S865	score1	Signor	15084608
	Q9WTK5 (Nfkb2)	S869	score1	Signor	15084608
	Q9Z1E3 (Nfkbia)	S32	score2	PhosphoSitePlus	17254973
	Q9Z1E3 (Nfkbia)	S36	score2	PhosphoSitePlus	17254973

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000036121 (mCHUK/iso:1/Phos:1)	pS176,pS180		PRO	16751795