iPTMnet Report for Q5ZPR3 (CD276)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5ZPR3 / CD276_HUMAN
Protein Name CD276 antigen precursor
Gene Name Name: CD276
Synonyms:B7H3;ORFNames:PSEC0249,UNQ309/PRO352;
Organism Homo sapiens (Human)

PRO ID PR:Q5ZPR3
DAG View
PRO Name CD276 antigen (human)
Definition A CD276 molecule that is encoded in the genome of human.
Short Label hCD276
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5ZPR3 (CD276) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N91 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N104 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...24190977
S106 Phosphorylation PhosphoSitePlus
C122 Methylation IEDB 31844290
K144 Ubiquitination PhosphoSitePlus
N215 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...24190977
T236 O-Glycosylation GlyGen 25813380
N322 N-Glycosylation GlyGen   UniProt 19159218
S324 Phosphorylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
N407 N-Glycosylation GlyGen   UniProt 19159218
S513 Phosphorylation PhosphoSitePlus
T515 Phosphorylation PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus
S525 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
K526 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T262 Phosphorylation HPRD 18452278
T265 Phosphorylation HPRD 18452278
S525 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S307 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S106 F106 Biomuta DOID:4159 / skin cancer [ cosmic ]
T262 S262 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T262 I262 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S307 R307 Biomuta DOID:1612 / breast cancer [ cosmic ]
N322 I322 Biomuta DOID:1324 / lung cancer [ cosmic ]
S324 F324 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
N407 Y407 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N407 K407 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S523 C523 Biomuta DOID:1612 / breast cancer [ cosmic ]
S525 R525 Biomuta DOID:1612 / breast cancer [ cosmic ]