iPTMnet Report for Q5XXA6 (ANO1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5XXA6 / ANO1_HUMAN
Protein Name Anoctamin-1
Gene Name Name: ANO1
Synonyms:DOG1;
Organism Homo sapiens (Human)

PRO ID PR:Q5XXA6
DAG View
PRO Name anoctamin-1 (human)
Definition An anoctamin-1 that is encoded in the genome of human.
Short Label hANO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5XXA6 (ANO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y7 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
T9 Phosphorylation PhosphoSitePlus   RLIMS-P 27212225
Y54 Phosphorylation PhosphoSitePlus
Y64 Phosphorylation PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
T88 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
K104 Methylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y119 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus   UniProt 24275569
S221 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
Y251 Phosphorylation PhosphoSitePlus
K261 Acetylation PhosphoSitePlus
Y302 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
Y314 Phosphorylation PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
K592 Ubiquitination PhosphoSitePlus
K941 Ubiquitination PhosphoSitePlus
K951 Ubiquitination PhosphoSitePlus
S974 Phosphorylation PhosphoSitePlus
S978 Phosphorylation PhosphoSitePlus
Y981 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 L8 Biomuta DOID:3571 / liver cancer [ cosmic ]
T9 M9 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T78 N78 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S107 L107 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y119 N119 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S221 F221 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K313 N313 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S466 Y466 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S555 F555 Biomuta DOID:4159 / skin cancer [ cosmic ]