iPTMnet Report for Q5XUX1 (FBXW9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5XUX1 / FBXW9_HUMAN
Protein Name F-box/WD repeat-containing protein 9
Gene Name Name: FBXW9
Synonyms:FBW9;
Organism Homo sapiens (Human)

PRO ID PR:Q5XUX1
DAG View
PRO Name F-box/WD repeat-containing protein 9 (human)
Definition An F-box/WD repeat-containing protein 9 that is encoded in the genome of human.
Short Label hFBXW9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5XUX1 (FBXW9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T13 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332, 24275569
S22 Phosphorylation PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T55 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S59 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S61 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S63 Phosphorylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
T281 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation HPRD 18452278
S39 Phosphorylation HPRD 18767875
T55 Phosphorylation HPRD 18669648
S61 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S18 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S18 W18 Biomuta DOID:1324 / lung cancer [ cosmic ]
S22 L22 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T24 A24 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T24 R24 Biomuta [ cosmic ]
S39 I39 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K287 N287 Biomuta DOID:363 / uterine cancer [ icgc ]
S383 P383 Biomuta DOID:3571 / liver cancer [ cosmic ]