iPTMnet Report for Q5VZV1 (METTL21C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VZV1 / MT21C_HUMAN
Protein Name Protein-lysine methyltransferase METTL21C
Gene Name Name: METTL21C
Synonyms:C13orf39;
Organism Homo sapiens (Human)

PRO ID PR:Q5VZV1
DAG View
PRO Name protein-lysine methyltransferase METTL21C (human)
Definition A protein-lysine methyltransferase METTL21C that is encoded in the genome of human.
Short Label hMETTL21C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VZV1 (METTL21C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
K224 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S45 F45 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K224 T224 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K224 Q224 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]