iPTMnet Report for Q5VZK9 (CARMIL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VZK9 / CARL1_HUMAN
Protein Name F-actin-uncapping protein LRRC16A
Gene Name Name: CARMIL1
Synonyms:CARMIL;
Organism Homo sapiens (Human)

PRO ID PR:Q5VZK9
DAG View
PRO Name F-actin-uncapping protein LRRC16A (human)
Definition An F-actin-uncapping protein LRRC16A that is encoded in the genome of human.
Short Label hCARMIL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VZK9 (CARMIL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S5 Phosphorylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
T112 Phosphorylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus   UniProt 23186163
T280 Phosphorylation PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
T599 Phosphorylation PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
Y660 Phosphorylation PhosphoSitePlus
K669 Methylation PhosphoSitePlus
K697 Ubiquitination PhosphoSitePlus
K718 Ubiquitination PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
K819 Ubiquitination PhosphoSitePlus
K833 Ubiquitination PhosphoSitePlus
S835 Phosphorylation PhosphoSitePlus
S869 Phosphorylation PhosphoSitePlus
K873 Ubiquitination PhosphoSitePlus
S880 Phosphorylation PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus
T902 Phosphorylation PhosphoSitePlus
T912 Phosphorylation PhosphoSitePlus
T916 Phosphorylation PhosphoSitePlus   UniProt 18669648, 24275569
S919 Phosphorylation PhosphoSitePlus
S923 Phosphorylation PhosphoSitePlus
S926 Phosphorylation PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus
S967 Phosphorylation PhosphoSitePlus
S968 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...19690332
K1036 Acetylation PhosphoSitePlus
S1039 Phosphorylation PhosphoSitePlus
S1043 Phosphorylation PhosphoSitePlus
S1047 Phosphorylation PhosphoSitePlus
S1049 Phosphorylation PhosphoSitePlus
S1064 Phosphorylation PhosphoSitePlus
S1067 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S1068 Phosphorylation PhosphoSitePlus
T1085 Phosphorylation PhosphoSitePlus
S1093 Phosphorylation PhosphoSitePlus
S1094 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1101 Phosphorylation PhosphoSitePlus
T1128 Phosphorylation PhosphoSitePlus
S1131 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation PhosphoSitePlus
S1150 Phosphorylation PhosphoSitePlus
S1151 Phosphorylation PhosphoSitePlus
S1165 Phosphorylation PhosphoSitePlus
T1228 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1254 Phosphorylation PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
S1280 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1288 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
S1290 Phosphorylation PhosphoSitePlus
S1291 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S1306 Phosphorylation PhosphoSitePlus
S1314 Phosphorylation PhosphoSitePlus
S1315 Phosphorylation PhosphoSitePlus   UniProt 21406692
S1319 Phosphorylation PhosphoSitePlus
S1324 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1331 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
Y1339 Phosphorylation PhosphoSitePlus
K1343 Ubiquitination PhosphoSitePlus
S1355 Phosphorylation PhosphoSitePlus
S1357 Phosphorylation PhosphoSitePlus
S1360 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S81 L81 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T112 S112 Biomuta DOID:3571 / liver cancer [ cosmic ]
T280 A280 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S415 F415 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
K656 N656 Biomuta DOID:363 / uterine cancer [ icgc ]
K718 Q718 Biomuta DOID:4159 / skin cancer [ cosmic ]
K873 N873 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S919 F919 Biomuta DOID:4159 / skin cancer [ icgc ]
S960 F960 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1049 F1049 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1064 Y1064 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1068 G1068 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T1085 M1085 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1093 F1093 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1094 L1094 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1131 T1131 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1261 F1261 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S1314 N1314 Biomuta [ cosmic ]
S1319 R1319 Biomuta DOID:363 / uterine cancer [ icgc ]
Y1339 N1339 Biomuta DOID:10283 / prostate cancer [ cosmic ]