iPTMnet Report for Q5VWQ8 (DAB2IP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VWQ8 / DAB2P_HUMAN
Protein Name Disabled homolog 2-interacting protein
Gene Name Name: DAB2IP
Synonyms:AF9Q34,AIP1,KIAA1743;
Organism Homo sapiens (Human)

PRO ID PR:Q5VWQ8
DAG View
PRO Name disabled homolog 2-interacting protein (human)
Definition A disabled homolog 2-interacting protein that is encoded in the genome of human.
Short Label hDAB2IP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VWQ8 (DAB2IP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K223 Acetylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
Y610 Phosphorylation PhosphoSitePlus
T670 Phosphorylation PhosphoSitePlus
S702 Phosphorylation phospho.ELM   PhosphoSitePlus 16964243
S722 Phosphorylation PhosphoSitePlus
S726 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S728 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 27858941, 19903888, 17389591
S728 Phosphorylation Q13546 (RIPK1) PhosphoSitePlus   Signor 27858941, 17389591
Y729 Phosphorylation phospho.ELM 18669648
S745 Phosphorylation PhosphoSitePlus
S747 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S763 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T790 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T799 Phosphorylation PhosphoSitePlus
T812 Phosphorylation PhosphoSitePlus
Y833 Phosphorylation PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus
S855 Phosphorylation PhosphoSitePlus
S858 Phosphorylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
S874 Phosphorylation PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus
S910 Phosphorylation PhosphoSitePlus
R932 Methylation PhosphoSitePlus
R934 Methylation PhosphoSitePlus
T935 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T942 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y945 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S949 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S950 Phosphorylation PhosphoSitePlus
S955 Phosphorylation phospho.ELM 18669648
S957 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S971 Phosphorylation PhosphoSitePlus   Signor 27858941
S971 Phosphorylation P31749 (AKT1) Signor 27858941
S972 Phosphorylation PhosphoSitePlus
S973 Phosphorylation PhosphoSitePlus
S974 Phosphorylation PhosphoSitePlus
S978 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S992 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S995 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1031 Phosphorylation PhosphoSitePlus
K1048 Ubiquitination PhosphoSitePlus
K1055 Ubiquitination PhosphoSitePlus
Y1059 Phosphorylation PhosphoSitePlus
T1061 Phosphorylation PhosphoSitePlus
S1108 Phosphorylation PhosphoSitePlus
S1126 Phosphorylation PhosphoSitePlus
K1136 Ubiquitination PhosphoSitePlus
S1140 Phosphorylation PhosphoSitePlus
S1150 Phosphorylation PhosphoSitePlus
T1153 Phosphorylation PhosphoSitePlus
S1168 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T531 Phosphorylation PhosphoSitePlus
T546 Phosphorylation PhosphoSitePlus
S578 Phosphorylation HPRD 16964243, 20068231
S602 Phosphorylation HPRD 18669648
Y605 Phosphorylation HPRD 18669648
S623 Phosphorylation HPRD 19651622, 18669648
S639 Phosphorylation HPRD 18669648
T666 Phosphorylation HPRD 18669648
T811 Phosphorylation HPRD 18669648
T818 Phosphorylation HPRD 18669648
Y821 Phosphorylation HPRD 18669648
S825 Phosphorylation HPRD 18669648
S831 Phosphorylation HPRD 18669648
S833 Phosphorylation HPRD 18669648
S854 Phosphorylation HPRD 19651622
S868 Phosphorylation HPRD 18669648, 20068231
S871 Phosphorylation HPRD 18669648, 20068231
S1044 Phosphorylation HPRD 19007248
Site PTM Type PTM Enzyme Score Source PMID
S674 Phosphorylation HPRD 16964243, 20068231
S698 Phosphorylation HPRD 18669648
Y701 Phosphorylation HPRD 18669648
S719 Phosphorylation HPRD 19651622, 18669648
S735 Phosphorylation HPRD 18669648
T762 Phosphorylation HPRD 18669648
T907 Phosphorylation HPRD 18669648
T914 Phosphorylation HPRD 18669648
Y917 Phosphorylation HPRD 18669648
S921 Phosphorylation HPRD 18669648
S927 Phosphorylation HPRD 18669648
S929 Phosphorylation HPRD 18669648
S950 Phosphorylation HPRD 19651622
S964 Phosphorylation HPRD 18669648, 20068231
S967 Phosphorylation HPRD 18669648, 20068231
K1128 Methylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9HCE7 (SMURF1) T145 Q5VWQ8 (DAB2IP) unknown eFIP 27036023


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T76 M76 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S122 F122 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K223 N223 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y605 H605 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y701 H701 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y729 H729 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T811 M811 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S842 L842 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S871 G871 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S874 N874 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T907 M907 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R932 P932 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R932 H932 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T935 M935 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S967 G967 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S971 F971 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S972 C972 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S974 F974 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S995 G995 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K1048 N1048 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y1059 D1059 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1108 F1108 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1153 I1153 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]