iPTMnet Report for Q5VW32 (BROX)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VW32 / BROX_HUMAN
Protein Name BRO1 domain-containing protein BROX precursor
Gene Name Name: BROX
Synonyms:BROFTI,C1orf58;
Organism Homo sapiens (Human)

PRO ID PR:Q5VW32
DAG View
PRO Name BRO1 domain-containing protein BROX (human)
Definition A BRO1 domain-containing protein BROX that is encoded in the genome of human.
Short Label hBROX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VW32 (BROX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K11 Ubiquitination PhosphoSitePlus
Y20 Phosphorylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
K91 Methylation PhosphoSitePlus
T136 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K237 Acetylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
K283 Acetylation PhosphoSitePlus   UniProt 19608861
K283 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
Y331 Phosphorylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y20 H20 Biomuta DOID:363 / uterine cancer [ icgc ]
Y20 C20 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y281 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K295 E295 Biomuta DOID:1324 / lung cancer [ cosmic ]