Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VVW2 / GARL3_HUMAN
Protein Name GTPase-activating Rap/Ran-GAP domain-like protein 3
Gene Name Name: GARNL3
Organism Homo sapiens (Human)

PRO ID PR:Q5VVW2
DAG View
PRO Name GTPase-activating Rap/Ran-GAP domain-like protein 3 (human)
Definition A GTPase-activating Rap/Ran-GAP domain-like protein 3 that is encoded in the genome of human.
Short Label hGARNL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VVW2 (GARNL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
T126 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
T158 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
K395 Acetylation PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
K617 Acetylation PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
S820 Phosphorylation PhosphoSitePlus
S824 Phosphorylation PhosphoSitePlus
T827 Phosphorylation PhosphoSitePlus
S869 Phosphorylation PhosphoSitePlus
S994 Phosphorylation PhosphoSitePlus
S996 Phosphorylation PhosphoSitePlus
S1005 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S51 F51 Biomuta DOID:4159 / skin cancer [ cosmic ]
S128 F128 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y155 C155 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T399 A399 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
K817 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S824 Y824 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S994 P994 Biomuta DOID:9256 / colorectal cancer [ cosmic ]