iPTMnet Report for Q5VVQ6 (YOD1)
Protein Information
| UniProt AC / UniProt ID | Q5VVQ6 / OTU1_HUMAN |
| Protein Name | Ubiquitin thioesterase OTU1 |
| Gene Name | Name: YOD1 Synonyms:DUBA8,HIN7,OTUD2;ORFNames:PRO0907; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q5VVQ6 |
| PRO Name | ubiquitin thioesterase OTU1 (human) |
| Definition | A ubiquitin thioesterase OTU1 that is encoded in the genome of human. |
| Short Label | hYOD1 |
| Category | organism-gene |
Q5VVQ6 (YOD1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T150 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K325 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T150 | I150 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T150 | A150 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View