iPTMnet Report for Q5VVJ2 (MYSM1)
Protein Information
| UniProt AC / UniProt ID | Q5VVJ2 / MYSM1_HUMAN |
| Protein Name | Deubiquitinase MYSM1 |
| Gene Name | Name: MYSM1 Synonyms:KIAA1915; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q5VVJ2 |
| PRO Name | deubiquitinase MYSM1 (human) |
| Definition | A deubiquitinase MYSM1 that is encoded in the genome of human. |
| Short Label | hMYSM1 |
| Category | organism-gene |
Q5VVJ2 (MYSM1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K84 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K98 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S110 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T112 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T175 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K187 | Sumoylation | score1 | PhosphoSitePlus | |||
| T197 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S218 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163, 18669648, ... | ||
| T226 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S234 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332, 18669648 | ||
| T236 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
| S242 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S267 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163 | ||
| K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K315 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K321 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S340 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
| K391 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T405 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K411 | Acetylation | score1 | PhosphoSitePlus | |||
| K533 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K675 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K90 | N90 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
| S118 | L118 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S149 | N149 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| S234 | F234 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S340 | F340 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
DAG View