iPTMnet Report for Q5VV67 (PPRC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VV67 / PPRC1_HUMAN
Protein Name Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
Gene Name Name: PPRC1
Synonyms:KIAA0595;
Organism Homo sapiens (Human)

PRO ID PR:Q5VV67
DAG View
PRO Name peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (human)
Definition A peroxisome proliferator-activated receptor gamma coactivator-related protein 1 that is encoded in the genome of human.
Short Label hPPRC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VV67 (PPRC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K166 Ubiquitination PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus   UniProt 23186163
C343 Methylation IEDB 31844290
S369 Phosphorylation PhosphoSitePlus
R373 Methylation IEDB 27503676
C408 Methylation IEDB 31844290
K411 Ubiquitination PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
C426 Methylation IEDB 31844290
K518 Acetylation PhosphoSitePlus
K520 Acetylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus   UniProt 20068231
S547 Phosphorylation PhosphoSitePlus
S548 Phosphorylation PhosphoSitePlus   UniProt 23186163
S737 Phosphorylation PhosphoSitePlus
S771 Phosphorylation PhosphoSitePlus
T785 Phosphorylation PhosphoSitePlus
S859 Phosphorylation PhosphoSitePlus
K1015 Sumoylation PhosphoSitePlus
S1063 Phosphorylation PhosphoSitePlus
S1076 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1101 Sumoylation PhosphoSitePlus
K1101 Ubiquitination PhosphoSitePlus
K1112 Acetylation PhosphoSitePlus
S1144 Phosphorylation PhosphoSitePlus
T1148 Phosphorylation PhosphoSitePlus
T1229 Phosphorylation PhosphoSitePlus
T1233 Phosphorylation PhosphoSitePlus
S1246 Phosphorylation PhosphoSitePlus
S1302 Phosphorylation PhosphoSitePlus
S1319 Phosphorylation PhosphoSitePlus
C1369 Methylation IEDB 31844290
S1377 Phosphorylation PhosphoSitePlus
S1381 Phosphorylation PhosphoSitePlus
T1391 Phosphorylation PhosphoSitePlus
S1411 Phosphorylation PhosphoSitePlus   UniProt 21406692
S1413 Phosphorylation PhosphoSitePlus   UniProt 21406692
S1429 Phosphorylation PhosphoSitePlus
S1434 Phosphorylation PhosphoSitePlus
S1441 Phosphorylation PhosphoSitePlus
S1443 Phosphorylation PhosphoSitePlus
S1444 Phosphorylation PhosphoSitePlus
S1445 Phosphorylation PhosphoSitePlus
S1446 Phosphorylation PhosphoSitePlus
S1447 Phosphorylation PhosphoSitePlus
S1450 Phosphorylation PhosphoSitePlus
S1451 Phosphorylation PhosphoSitePlus
S1476 Phosphorylation PhosphoSitePlus
S1480 Phosphorylation PhosphoSitePlus
S1481 Phosphorylation PhosphoSitePlus
S1482 Phosphorylation PhosphoSitePlus
S1483 Phosphorylation PhosphoSitePlus
S1484 Phosphorylation PhosphoSitePlus
S1485 Phosphorylation PhosphoSitePlus
S1486 Phosphorylation PhosphoSitePlus
S1487 Phosphorylation PhosphoSitePlus
S1488 Phosphorylation PhosphoSitePlus
S1489 Phosphorylation PhosphoSitePlus
S1490 Phosphorylation PhosphoSitePlus
S1491 Phosphorylation PhosphoSitePlus
S1492 Phosphorylation PhosphoSitePlus
S1493 Phosphorylation PhosphoSitePlus
S1494 Phosphorylation PhosphoSitePlus
S1495 Phosphorylation PhosphoSitePlus
S1497 Phosphorylation PhosphoSitePlus
S1498 Phosphorylation PhosphoSitePlus
S1499 Phosphorylation PhosphoSitePlus
S1503 Phosphorylation PhosphoSitePlus
S1505 Phosphorylation PhosphoSitePlus
S1507 Phosphorylation PhosphoSitePlus
S1512 Phosphorylation PhosphoSitePlus
K1549 Ubiquitination PhosphoSitePlus
T1555 Phosphorylation PhosphoSitePlus
S1557 Phosphorylation PhosphoSitePlus
K1603 Ubiquitination PhosphoSitePlus
S1628 Phosphorylation PhosphoSitePlus
K1643 Ubiquitination PhosphoSitePlus
K1645 Sumoylation PhosphoSitePlus
K1645 Ubiquitination PhosphoSitePlus
K1656 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S536 Phosphorylation HPRD 20068231
S1076 Phosphorylation HPRD 19664995
S1319 Phosphorylation HPRD 20068231
S1413 Phosphorylation HPRD 19664995
S1503 Phosphorylation HPRD 20068231
S1505 Phosphorylation HPRD 20068231
S1507 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S369 F369 Biomuta [ cosmic ]
S369 C369 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R373 W373 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S536 G536 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
T1148 I1148 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1377 F1377 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1445 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S1447 L1447 Biomuta DOID:363 / uterine cancer [ icgc ]
S1450 L1450 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1451 Y1451 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1480 F1480 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1484 L1484 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
S1488 F1488 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1490 L1490 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ]
S1492 F1492 Biomuta [ cosmic ]
S1497 P1497 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S1499 F1499 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1512 C1512 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]