iPTMnet Report for Q5VV41 (ARHGEF16)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VV41 / ARHGG_HUMAN
Protein Name Rho guanine nucleotide exchange factor 16
Gene Name Name: ARHGEF16
Synonyms:EPHEXIN4,NBR;
Organism Homo sapiens (Human)

PRO ID PR:Q5VV41
DAG View
PRO Name Rho guanine nucleotide exchange factor 16 (human)
Definition A Rho guanine nucleotide exchange factor 16 that is encoded in the genome of human.
Short Label hARHGEF16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VV41 (ARHGEF16) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 21406692
S6 Phosphorylation PhosphoSitePlus   UniProt 21406692
S8 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S41 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T101 Phosphorylation PhosphoSitePlus
S107 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18220336, ...18669648, 20068231
S129 Phosphorylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
K159 Methylation PhosphoSitePlus
S174 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K176 Ubiquitination PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
S191 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S208 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
K210 Ubiquitination PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
S227 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S230 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S240 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S394 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
S499 Phosphorylation IEDB   PhosphoSitePlus 35494241
S565 Phosphorylation PhosphoSitePlus
S576 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S577 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S578 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K628 Ubiquitination PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 19651622, 20068231
S41 Phosphorylation HPRD 18669648, 20068231
S107 Phosphorylation HPRD 18767875, 18669648, 20068231
S174 Phosphorylation HPRD 18669648, 20068231
S185 Phosphorylation HPRD 20068231
S191 Phosphorylation HPRD 18669648, 20068231
S208 Phosphorylation HPRD 18767875, 18669648
S227 Phosphorylation HPRD 18669648
S230 Phosphorylation HPRD 18669648, 18491316
S240 Phosphorylation HPRD 18669648
S576 Phosphorylation HPRD 17322306, 18669648, 20068231
S577 Phosphorylation HPRD 18669648
S578 Phosphorylation HPRD 19651622, 18669648


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P29317 (EPHA2) S897 Q5VV41 (ARHGEF16) unknown eFIP 23772378