iPTMnet Report for Q5VTL8 (PRPF38B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VTL8 / PR38B_HUMAN
Protein Name Pre-mRNA-splicing factor 38B
Gene Name Name: PRPF38B
Organism Homo sapiens (Human)

PRO ID PR:Q5VTL8
DAG View
PRO Name pre-mRNA-splicing factor 38B (human)
Definition A pre-mRNA-splicing factor 38B that is encoded in the genome of human.
Short Label hPRPF38B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VTL8 (PRPF38B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S5 Phosphorylation PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
K227 Acetylation PhosphoSitePlus   UniProt 19608861
K227 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
R253 Methylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S266 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S268 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S272 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S276 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus   UniProt 23186163
S289 Phosphorylation PhosphoSitePlus
S290 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S318 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S320 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983
S340 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S385 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S448 Phosphorylation PhosphoSitePlus   UniProt 20068231
S471 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus   UniProt 21406692
S475 Phosphorylation PhosphoSitePlus   UniProt 21406692
T479 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus   UniProt 21406692
S485 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
S493 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S503 Phosphorylation PhosphoSitePlus
S527 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 16083285, 23186163, ...16964243, 15302935, 21406692, 18669648, 20068231, 17081983
S529 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 20068231, 17081983
S534 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17525332, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 19413330, 20068231
S40 Phosphorylation HPRD 20068231
T121 Phosphorylation HPRD 19413330
T150 Phosphorylation HPRD 20068231
T152 Phosphorylation HPRD 20068231
S154 Phosphorylation HPRD 20068231
S266 Phosphorylation HPRD 20068231
S268 Phosphorylation HPRD 20068231, 17924679
S288 Phosphorylation HPRD 19651622
S289 Phosphorylation HPRD 18452278
S290 Phosphorylation HPRD 20068231, 18452278
S318 Phosphorylation HPRD 20068231
S320 Phosphorylation HPRD 20068231
S448 Phosphorylation HPRD 20068231
S471 Phosphorylation HPRD 19651622, 20068231
S473 Phosphorylation HPRD 19651622, 20068231
S475 Phosphorylation HPRD 19651622, 20068231
S481 Phosphorylation HPRD 19651622
S491 Phosphorylation HPRD 20068231
S493 Phosphorylation HPRD 19651622, 20068231
S527 Phosphorylation HPRD 16964243, 18767875, 15302935, ...18452278, 19651622, 18669648, 20166139, 20068231
S529 Phosphorylation HPRD 16083285, 16964243, 18452278, ...19651622, 18669648, 20166139, 20068231
S534 Phosphorylation HPRD 19651622, 17525332, 18669648, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T150 P150 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S154 Y154 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y156 H156 Biomuta DOID:1324 / lung cancer [ cosmic ]
K227 T227 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S276 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S288 F288 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S340 N340 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S481 R481 Biomuta DOID:1612 / breast cancer [ cosmic ]
S493 I493 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]