iPTMnet Report for Q5VTE6 (ANGEL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VTE6 / ANGE2_HUMAN
Protein Name Protein angel homolog 2
Gene Name Name: ANGEL2
Synonyms:KIAA0759L;
Organism Homo sapiens (Human)

PRO ID PR:Q5VTE6
DAG View
PRO Name protein angel homolog 2 (human)
Definition A protein angel homolog 2 that is encoded in the genome of human.
Short Label hANGEL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VTE6 (ANGEL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R18 Methylation PhosphoSitePlus
R20 Methylation PhosphoSitePlus
Y21 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
R44 Methylation PhosphoSitePlus
R72 Methylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K152 Acetylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K157 Sumoylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
Y187 Phosphorylation PhosphoSitePlus
C241 Methylation IEDB 31844290
K259 Methylation PhosphoSitePlus
K368 Sumoylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
R387 Methylation PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
Y483 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K143 E143 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y187 C187 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
R387 Q387 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R387 W387 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K419 N419 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]