iPTMnet Report for Q5VT66 (MTARC1)
Protein Information
| UniProt AC / UniProt ID | Q5VT66 / MARC1_HUMAN |
| Protein Name | Mitochondrial amidoxime-reducing component 1 |
| Gene Name | Name: MTARC1 Synonyms:MARC1,MOSC1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q5VT66 |
| PRO Name | mitochondrial amidoxime-reducing component 1 (human) |
| Definition | A mitochondrial amidoxime-reducing component 1 that is encoded in the genome of human. |
| Short Label | hMTARC1 |
| Category | organism-gene |
Q5VT66 (MTARC1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score1 | UniProt | 25255805, 25807930 | ||
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R111 | Methylation | score1 | PhosphoSitePlus | |||
| K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K174 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K230 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K265 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K288 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S296 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y297 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S303 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K306 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y317 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R111 | H111 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| R111 | C111 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] | |
| K202 | N202 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View