iPTMnet Report for Q5VT52 (RPRD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VT52 / RPRD2_HUMAN
Protein Name Regulation of nuclear pre-mRNA domain-containing protein 2
Gene Name Name: RPRD2
Synonyms:KIAA0460;ORFNames:HSPC099;
Organism Homo sapiens (Human)

PRO ID PR:Q5VT52
DAG View
PRO Name regulation of nuclear pre-mRNA domain-containing protein 2 (human)
Definition A regulation of nuclear pre-mRNA domain-containing protein 2 that is encoded in the genome of human.
Short Label hRPRD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VT52 (RPRD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 25489052
S15 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus   UniProt 23186163
S26 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
T172 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S173 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T174 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
K177 Ubiquitination PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K249 Acetylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
Y278 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
R298 Methylation PhosphoSitePlus
S356 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
T358 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 21406692, 23186163, ...17081983
T363 Phosphorylation PhosphoSitePlus
S374 O-Glycosylation GlyGen 22661428
S374 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 19367720, 18669648, 24275569, 19690332, 20068231
S396 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S399 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S399 Phosphorylation PhosphoSitePlus
T400 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S401 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S401 Phosphorylation PhosphoSitePlus
T404 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T407 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S411 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S414 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T417 Phosphorylation PhosphoSitePlus
T422 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 32938750, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T424 O-Glycosylation GlyGen 29249144
T426 O-Glycosylation GlyGen 29249144
T426 Phosphorylation PhosphoSitePlus
S436 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S438 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S438 Phosphorylation PhosphoSitePlus
S440 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S440 Phosphorylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
T470 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S473 Phosphorylation PhosphoSitePlus   UniProt 19690332, 20068231
S476 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S476 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S479 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T482 O-Glycosylation GlyGen 32574038
T482 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 20068231
T484 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T484 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S485 O-Glycosylation GlyGen 34846842
S485 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S487 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S487 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T490 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T490 Phosphorylation PhosphoSitePlus
S491 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T495 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T495 Phosphorylation PhosphoSitePlus
T500 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T501 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T502 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S503 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S512 O-Glycosylation GlyGen 34846842, 32574038
S512 Phosphorylation PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
T517 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T528 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S540 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S545 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T547 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S554 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S558 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S560 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T561 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S562 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S564 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S564 Phosphorylation PhosphoSitePlus   UniProt 24275569
T568 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T572 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S580 Phosphorylation PhosphoSitePlus
S581 Phosphorylation PhosphoSitePlus
S589 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S589 Phosphorylation PhosphoSitePlus
Y592 Phosphorylation PhosphoSitePlus
S593 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 15302935, 18669648, ...19690332, 20068231
S596 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S596 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S597 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 32938750, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S597 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T598 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T598 Phosphorylation PhosphoSitePlus   UniProt 19690332
S599 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T604 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S605 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S607 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S610 Phosphorylation PhosphoSitePlus
S614 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S614 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 15302935, ...18669648, 19690332, 20068231
S628 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T637 O-Glycosylation GlyGen 32574038
S638 Phosphorylation PhosphoSitePlus
T644 O-Glycosylation GlyGen 32574038
S661 Phosphorylation PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus   UniProt 23186163
T664 Phosphorylation PhosphoSitePlus
S665 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163, ...19690332
S667 Phosphorylation PhosphoSitePlus
K671 Acetylation PhosphoSitePlus
K671 Ubiquitination PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus
S714 Phosphorylation PhosphoSitePlus
T715 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus   UniProt 23186163
T723 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 24275569, 20068231
S730 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 15302935
T732 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 18220336
T734 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S746 Phosphorylation PhosphoSitePlus
S758 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 15302935, ...16964243
S761 Phosphorylation PhosphoSitePlus
S762 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S762 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16964243
T763 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S765 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
T767 Phosphorylation PhosphoSitePlus
S769 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S777 Phosphorylation PhosphoSitePlus
Y778 Phosphorylation PhosphoSitePlus
S785 Phosphorylation PhosphoSitePlus
S796 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S798 Phosphorylation PhosphoSitePlus
S804 Phosphorylation PhosphoSitePlus
S817 Phosphorylation PhosphoSitePlus   UniProt 23186163
S826 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
K862 Acetylation PhosphoSitePlus
S864 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S864 Phosphorylation PhosphoSitePlus
T866 Phosphorylation PhosphoSitePlus
T867 O-Glycosylation GlyGen 31373491
T867 Phosphorylation PhosphoSitePlus
Y869 Phosphorylation PhosphoSitePlus
S899 Phosphorylation phospho.ELM 18669648
S900 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S907 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S908 Phosphorylation PhosphoSitePlus
S909 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...18220336
S928 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S930 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S932 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S936 Phosphorylation PhosphoSitePlus
T939 Phosphorylation PhosphoSitePlus
Y962 Phosphorylation PhosphoSitePlus
S965 Phosphorylation PhosphoSitePlus   UniProt 23186163
S973 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S973 Phosphorylation PhosphoSitePlus
S976 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S976 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T980 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T980 Phosphorylation PhosphoSitePlus
T985 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T990 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S991 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S999 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
T1003 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
K1014 Ubiquitination PhosphoSitePlus
S1017 Phosphorylation PhosphoSitePlus
S1021 Phosphorylation PhosphoSitePlus
S1031 Phosphorylation PhosphoSitePlus
K1032 Acetylation PhosphoSitePlus
K1032 Ubiquitination PhosphoSitePlus
T1034 Phosphorylation PhosphoSitePlus
S1068 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29249144, 22661428, 29237092, 27114449, 34725712, 31373491, 32119511, 31637018, 32574038, 35132862, 34931806, 29351928, 28657654, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 20068230
S1068 Phosphorylation PhosphoSitePlus
S1069 O-Glycosylation GlyGen 31373491
S1069 Phosphorylation PhosphoSitePlus
S1070 Phosphorylation PhosphoSitePlus
C1071 S-Nitrosylation dbSNO 26338901
Y1090 Phosphorylation PhosphoSitePlus
S1092 Phosphorylation PhosphoSitePlus
S1099 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...27869121, 19690332, 20068231
S1108 Phosphorylation PhosphoSitePlus
R1117 Methylation PhosphoSitePlus
S1180 Phosphorylation PhosphoSitePlus
S1183 Phosphorylation PhosphoSitePlus
S1185 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1197 Phosphorylation PhosphoSitePlus
S1214 Phosphorylation PhosphoSitePlus
S1237 Phosphorylation PhosphoSitePlus
R1366 Methylation PhosphoSitePlus   UniProt 24129315
S1368 Phosphorylation PhosphoSitePlus
T1370 Phosphorylation PhosphoSitePlus
T1406 Phosphorylation PhosphoSitePlus
S1408 Phosphorylation PhosphoSitePlus
R1415 Methylation PhosphoSitePlus
R1418 Methylation PhosphoSitePlus
R1422 Methylation PhosphoSitePlus
R1424 Methylation PhosphoSitePlus   UniProt 24129315
R1430 Methylation PhosphoSitePlus   UniProt 24129315
R1454 Methylation PhosphoSitePlus
R1460 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S356 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
T358 Phosphorylation HPRD 19651622, 15302935, 20068231, ...18452278
S374 Phosphorylation HPRD 18767875, 15302935, 18452278, ...19651622, 18669648, 20166139, 20068231
T426 Phosphorylation HPRD 19413330
S440 Phosphorylation HPRD 20068231
S473 Phosphorylation HPRD 20068231
S476 Phosphorylation HPRD 19413330, 18669648, 20068231
S479 Phosphorylation HPRD 19413330, 18669648
T482 Phosphorylation HPRD 19413330, 18669648, 17081983, ...20068231
T484 Phosphorylation HPRD 19413330, 18669648, 20068231
S485 Phosphorylation HPRD 19651622, 18669648, 20068231
S487 Phosphorylation HPRD 18669648
S491 Phosphorylation HPRD 18669648, 20068231
T517 Phosphorylation HPRD 18669648, 20068231
S589 Phosphorylation HPRD 20068231
S593 Phosphorylation HPRD 19413330, 18491316, 20058876, ...15302935, 19664994, 19664995, 18452278, 19651622, 18669648, 20166139, 20068231
S596 Phosphorylation HPRD 19413330, 18669648, 20068231
S597 Phosphorylation HPRD 19413330, 18669648
T598 Phosphorylation HPRD 20068231
S599 Phosphorylation HPRD 20068231
S602 Phosphorylation HPRD 20068231
S605 Phosphorylation HPRD 18669648
S607 Phosphorylation HPRD 20068231
S614 Phosphorylation HPRD 19413330, 17322306, 16964243, ...18767875, 19664995, 19651622, 18669648, 20068231
T664 Phosphorylation HPRD 19413330, 17081983, 19664995
S665 Phosphorylation HPRD 19413330, 15302935, 19664995, ...18452278, 18669648, 20068231
S667 Phosphorylation HPRD 17081983, 20068231, 19415658
T723 Phosphorylation HPRD 17081983, 18767875, 19664994, ...19664995, 19651622, 18669648, 19415658, 20068231, 18212344
S730 Phosphorylation HPRD 19651622, 18669648, 20068231
T732 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
T734 Phosphorylation HPRD 18669648, 18452278
S758 Phosphorylation HPRD 18669648, 15302935, 16964243
S762 Phosphorylation HPRD 16964243
T763 Phosphorylation HPRD 18669648
S769 Phosphorylation HPRD 18669648, 18452278
T788 Phosphorylation HPRD 20068231
S796 Phosphorylation HPRD 19651622
S817 Phosphorylation HPRD 17525332
S826 Phosphorylation HPRD 18669648, 20068231
S899 Phosphorylation HPRD 18669648
S900 Phosphorylation HPRD 18669648
S907 Phosphorylation HPRD 18669648, 19664995, 20068231
S909 Phosphorylation HPRD 18669648, 19664995, 20068231
S928 Phosphorylation HPRD 19651622, 18669648, 20068231
S930 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S932 Phosphorylation HPRD 19651622, 18669648
S965 Phosphorylation HPRD 20068231
S976 Phosphorylation HPRD 18669648, 20068231, 17924679
S1017 Phosphorylation HPRD 20068231
S1099 Phosphorylation HPRD 18669648, 20068231, 18452278
S1108 Phosphorylation HPRD 20068231
S1185 Phosphorylation HPRD 18669648
T1406 Phosphorylation HPRD 19664995
S1408 Phosphorylation HPRD 19664995
Site PTM Type PTM Enzyme Score Source PMID
K151 Ubiquitination PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
S902 Phosphorylation PhosphoSitePlus
S904 Phosphorylation PhosphoSitePlus
S923 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S173 Y173 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K293 E293 Biomuta DOID:3571 / liver cancer [ cosmic ]
T294 I294 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R298 Q298 Biomuta DOID:2394 / ovarian cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
R298 L298 Biomuta DOID:1324 / lung cancer [ cosmic ]
S374 L374 Biomuta DOID:1324 / lung cancer [ cosmic ]
T404 I404 Biomuta DOID:2394 / ovarian cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ]
T426 N426 Biomuta DOID:363 / uterine cancer [ icgc ]
S436 Y436 Biomuta DOID:363 / uterine cancer [ icgc ]
S440 F440 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S473 G473 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S487 R487 Biomuta DOID:1324 / lung cancer [ cosmic ]
T490 I490 Biomuta DOID:1319 / brain cancer [ cosmic ]
S491 G491 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S560 R560 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T561 P561 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S562 T562 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S564 A564 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T572 N572 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T572 A572 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y592 C592 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S597 T597 Biomuta DOID:1324 / lung cancer [ cosmic ]
S599 Y599 Biomuta DOID:1319 / brain cancer [ icgc ]
T604 A604 Biomuta DOID:263 / kidney cancer [ cosmic ]
T637 P637 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S661 L661 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S758 G758 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S785 Y785 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S826 Y826 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S900 N900 Biomuta DOID:4159 / skin cancer [ cosmic ]
S909 P909 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S936 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S965 F965 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S973 F973 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S976 F976 Biomuta DOID:4159 / skin cancer [ cosmic ]
T985 A985 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T985 M985 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K1014 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1031 N1031 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1070 C1070 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
R1117 K1117 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R1366 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
T1406 A1406 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1408 G1408 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R1415 W1415 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R1418 Q1418 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R1418 W1418 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]