iPTMnet Report for Q5VIR6 (VPS53)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VIR6 / VPS53_HUMAN
Protein Name Vacuolar protein sorting-associated protein 53 homolog
Gene Name Name: VPS53
ORFNames:PP13624;
Organism Homo sapiens (Human)

PRO ID PR:Q5VIR6
DAG View
PRO Name vacuolar protein sorting-associated protein 53 homolog (human)
Definition A vacuolar protein sorting-associated protein 53 that is encoded in the genome of human.
Short Label hVPS53
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VIR6 (VPS53) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K110 Acetylation UniProt 19608861
C321 Methylation IEDB 31844290
K360 Acetylation UniProt 19608861
S377 Phosphorylation UniProt 18691976
T391 Phosphorylation UniProt 18691976
S580 Phosphorylation UniProt 20068231
C667 Methylation IEDB 31844290
S712 Phosphorylation PhosphoSitePlus
S714 Phosphorylation PhosphoSitePlus
S715 Phosphorylation PhosphoSitePlus
T734 Phosphorylation PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K102 Ubiquitination PhosphoSitePlus
K110 Acetylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
K360 Acetylation PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
T371 Phosphorylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
T391 Phosphorylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S348 Phosphorylation HPRD 18691976, 20068231
S352 Phosphorylation HPRD 18691976
T362 Phosphorylation HPRD 18691976
S551 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S348 F348 Biomuta DOID:2531 / hematologic cancer [ cosmic ]