iPTMnet Report for Q5U5Q3 (MEX3C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5U5Q3 / MEX3C_HUMAN
Protein Name RNA-binding E3 ubiquitin-protein ligase MEX3C
Gene Name Name: MEX3C
Synonyms:RKHD2,RNF194;ORFNames:BM-013;
Organism Homo sapiens (Human)

PRO ID PR:Q5U5Q3
DAG View
PRO Name RNA-binding E3 ubiquitin-protein ligase MEX3C (human)
Definition An RNA-binding protein MEX3C that is encoded in the genome of human.
Short Label hMEX3C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5U5Q3 (MEX3C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S88 Phosphorylation PhosphoSitePlus   UniProt 23186163
S145 Phosphorylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
T268 Phosphorylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
S320 Phosphorylation HPRD   PhosphoSitePlus 19664995
T358 Phosphorylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
S537 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163
S540 Phosphorylation HPRD   PhosphoSitePlus 19651622
T541 Phosphorylation PhosphoSitePlus
S545 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
T547 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K228 E228 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K228 N228 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T358 I358 Biomuta DOID:9256 / colorectal cancer [ cosmic ]