iPTMnet Report for Q5THR3 (EFCAB6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5THR3 / EFCB6_HUMAN
Protein Name EF-hand calcium-binding domain-containing protein 6
Gene Name Name: EFCAB6
Synonyms:DJBP,KIAA1672;
Organism Homo sapiens (Human)

PRO ID PR:Q5THR3
DAG View
PRO Name EF-hand calcium-binding domain-containing protein 6 (human)
Definition An EF-hand calcium-binding domain-containing protein 6 that is encoded in the genome of human.
Short Label hEFCAB6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5THR3 (EFCAB6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T107 Phosphorylation IEDB   PhosphoSitePlus 27869121
T158 Phosphorylation PhosphoSitePlus
K169 Acetylation PhosphoSitePlus
K172 Acetylation PhosphoSitePlus
K175 Acetylation PhosphoSitePlus
K179 Acetylation PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
S296 O-Glycosylation GlyGen 30620550
K297 Acetylation PhosphoSitePlus
K301 Acetylation PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
Y510 Phosphorylation PhosphoSitePlus
T521 Phosphorylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus
Y877 Phosphorylation PhosphoSitePlus
K911 Acetylation PhosphoSitePlus
T952 Phosphorylation PhosphoSitePlus
T1175 Phosphorylation PhosphoSitePlus
S1176 Phosphorylation PhosphoSitePlus
Y1178 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T158 Phosphorylation HPRD 19664994
Site PTM Type PTM Enzyme Score Source PMID
T6 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K172 N172 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K188 T188 Biomuta DOID:363 / uterine cancer [ icgc ]
S296 L296 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K301 R301 Biomuta DOID:3571 / liver cancer [ cosmic ]
K301 N301 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T424 I424 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T1175 A1175 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1178 H1178 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]