iPTMnet Report for Q5THJ4 (VPS13D)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5THJ4 / VP13D_HUMAN
Protein Name Intermembrane lipid transfer protein VPS13D
Gene Name Name: VPS13D
Synonyms:KIAA0453;
Organism Homo sapiens (Human)

PRO ID PR:Q5THJ4
DAG View
PRO Name intermembrane lipid transfer protein VPS13D (human)
Definition An intermembrane lipid transfer protein VPS13D that is encoded in the genome of human.
Short Label hVPS13D
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5THJ4 (VPS13D) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y17 Phosphorylation PhosphoSitePlus
Y132 Phosphorylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
T480 Phosphorylation IEDB 35494241
S545 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
S583 O-Glycosylation GlyGen 31492838, 28657654, 35289036
S583 Phosphorylation PhosphoSitePlus
S585 O-Glycosylation GlyGen 31492838, 28657654, 35289036
T590 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
Y661 Phosphorylation PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K705 Ubiquitination PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
Y768 Phosphorylation PhosphoSitePlus
T770 Phosphorylation PhosphoSitePlus
T791 Phosphorylation PhosphoSitePlus
T911 Phosphorylation PhosphoSitePlus
S926 Phosphorylation PhosphoSitePlus
S930 Phosphorylation PhosphoSitePlus
T935 Phosphorylation PhosphoSitePlus
S1027 Phosphorylation PhosphoSitePlus
S1034 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1038 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1042 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231, ...18220336
S1062 Phosphorylation PhosphoSitePlus
S1067 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K1192 Ubiquitination PhosphoSitePlus
S1341 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1478 Phosphorylation PhosphoSitePlus
S1511 Phosphorylation PhosphoSitePlus
S1573 Phosphorylation PhosphoSitePlus
S1598 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1603 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1685 Phosphorylation PhosphoSitePlus
S1698 Phosphorylation PhosphoSitePlus
S1699 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1709 Phosphorylation PhosphoSitePlus
S1712 Phosphorylation PhosphoSitePlus
S1724 Phosphorylation PhosphoSitePlus
S1727 Phosphorylation PhosphoSitePlus
T1743 Phosphorylation PhosphoSitePlus
S1744 Phosphorylation PhosphoSitePlus
Y1758 Phosphorylation PhosphoSitePlus
T1761 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...24275569
S1765 Phosphorylation PhosphoSitePlus   UniProt 24275569
T1767 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1862 Phosphorylation PhosphoSitePlus
S1865 Phosphorylation PhosphoSitePlus
T1873 Phosphorylation PhosphoSitePlus
T1889 Phosphorylation PhosphoSitePlus
T1890 Phosphorylation PhosphoSitePlus
S1891 Phosphorylation PhosphoSitePlus
S2038 Phosphorylation PhosphoSitePlus
S2039 Phosphorylation PhosphoSitePlus
S2079 Phosphorylation PhosphoSitePlus
T2081 Phosphorylation PhosphoSitePlus
S2087 Phosphorylation PhosphoSitePlus
S2114 Phosphorylation PhosphoSitePlus
T2126 O-Glycosylation GlyGen 31492838, 28657654, 35289036
Y2175 Phosphorylation PhosphoSitePlus
K2208 Ubiquitination PhosphoSitePlus
S2352 Phosphorylation PhosphoSitePlus
T2371 Phosphorylation PhosphoSitePlus
S2434 Phosphorylation PhosphoSitePlus
S2435 Phosphorylation PhosphoSitePlus   UniProt 21406692, 19690332
S2436 Phosphorylation PhosphoSitePlus
S2438 Phosphorylation PhosphoSitePlus
S2455 Phosphorylation PhosphoSitePlus
K2657 Ubiquitination PhosphoSitePlus
S2671 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S2682 Phosphorylation PhosphoSitePlus
S2684 Phosphorylation PhosphoSitePlus
S2687 Phosphorylation PhosphoSitePlus
T2688 Phosphorylation PhosphoSitePlus
S2692 Phosphorylation PhosphoSitePlus
Y2812 Phosphorylation PhosphoSitePlus
Y2823 Phosphorylation PhosphoSitePlus
S2861 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2864 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y2873 Phosphorylation PhosphoSitePlus
S2983 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2989 Ubiquitination PhosphoSitePlus
K3001 Ubiquitination PhosphoSitePlus
S3010 Phosphorylation PhosphoSitePlus
K3129 Ubiquitination PhosphoSitePlus
K3302 Ubiquitination PhosphoSitePlus
S3319 Phosphorylation PhosphoSitePlus
Y3391 Phosphorylation PhosphoSitePlus
Y3403 Phosphorylation PhosphoSitePlus
T3435 Phosphorylation PhosphoSitePlus
S3439 Phosphorylation PhosphoSitePlus
S3440 Phosphorylation PhosphoSitePlus
R3518 Methylation PhosphoSitePlus
K3524 Acetylation PhosphoSitePlus   UniProt 19608861
S3628 Phosphorylation PhosphoSitePlus
T3691 Phosphorylation PhosphoSitePlus
Y3695 Phosphorylation PhosphoSitePlus
R3770 Methylation PhosphoSitePlus
S3777 Phosphorylation PhosphoSitePlus
S3800 Phosphorylation PhosphoSitePlus
K3817 Ubiquitination PhosphoSitePlus
T3924 Phosphorylation PhosphoSitePlus
Y3927 Phosphorylation PhosphoSitePlus
K3972 Ubiquitination PhosphoSitePlus
T3973 Phosphorylation PhosphoSitePlus
T4102 Phosphorylation PhosphoSitePlus
S4106 Phosphorylation PhosphoSitePlus
S4108 Phosphorylation PhosphoSitePlus
K4318 Acetylation PhosphoSitePlus
K4325 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S545 Phosphorylation HPRD 20068231
S546 Phosphorylation HPRD 20068231
S549 Phosphorylation HPRD 20068231
T590 Phosphorylation HPRD 18452278
S592 Phosphorylation HPRD 18452278
S1038 Phosphorylation HPRD 19651622, 20068231
S1042 Phosphorylation HPRD 19651622, 20068231
S1045 Phosphorylation HPRD 17081983
S1341 Phosphorylation HPRD 18491316
S1724 Phosphorylation HPRD 19651622
T1743 Phosphorylation HPRD 19651622
S1744 Phosphorylation HPRD 19651622
T1761 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20068231
S1765 Phosphorylation HPRD 19413330, 19651622
T1767 Phosphorylation HPRD 19651622, 18669648, 20068231
S2079 Phosphorylation HPRD 19413330
T2081 Phosphorylation HPRD 19413330
S2087 Phosphorylation HPRD 18491316
S2435 Phosphorylation HPRD 19651622
T4102 Phosphorylation HPRD 18452278
S4106 Phosphorylation HPRD 18452278
S4108 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S545 Phosphorylation HPRD 20068231
S546 Phosphorylation HPRD 20068231
S549 Phosphorylation HPRD 20068231
T590 Phosphorylation HPRD 18452278
S592 Phosphorylation HPRD 18452278
S1038 Phosphorylation HPRD 19651622, 20068231
S1042 Phosphorylation HPRD 19651622, 20068231
S1045 Phosphorylation HPRD 17081983
S1341 Phosphorylation HPRD 18491316
S1724 Phosphorylation HPRD 19651622
T1743 Phosphorylation HPRD 19651622
S1744 Phosphorylation HPRD 19651622
T1761 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20068231
S1765 Phosphorylation HPRD 19413330, 19651622
T1767 Phosphorylation HPRD 19651622, 18669648, 20068231
S2079 Phosphorylation HPRD 19413330
T2081 Phosphorylation HPRD 19413330
S2087 Phosphorylation HPRD 18491316
S2435 Phosphorylation HPRD 19651622
T4077 Phosphorylation HPRD 18452278
S4081 Phosphorylation HPRD 18452278
S4083 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S545 F545 Biomuta DOID:4159 / skin cancer [ cosmic, cosmic, cosmic ] DOID:2174 / ocular cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S1067 L1067 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1341 L1341 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2174 / ocular cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S1598 I1598 Biomuta DOID:363 / uterine cancer [ cosmic ]
T1767 S1767 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S2079 F2079 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2436 N2436 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2455 F2455 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S2455 P2455 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S2684 F2684 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2688 I2688 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2692 N2692 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K3129 E3129 Biomuta DOID:1319 / brain cancer [ cosmic ]
S3319 C3319 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T3435 P3435 Biomuta DOID:1612 / breast cancer [ cosmic ]
S3440 T3440 Biomuta DOID:3571 / liver cancer [ cosmic ]
R3518 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R3518 Q3518 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T3691 S3691 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y3695 C3695 Biomuta DOID:1319 / brain cancer [ cosmic ]
R3770 K3770 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S3777 F3777 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3800 N3800 Biomuta DOID:1612 / breast cancer [ cosmic ]