iPTMnet Report for Q5TGY1 (TMCO4)
Protein Information
| UniProt AC / UniProt ID | Q5TGY1 / TMCO4_HUMAN |
| Protein Name | Transmembrane and coiled-coil domain-containing protein 4 |
| Gene Name | Name: TMCO4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q5TGY1 |
| PRO Name | transmembrane and coiled-coil domain-containing protein 4 (human) |
| Definition | A transmembrane and coiled-coil domain-containing protein 4 that is encoded in the genome of human. |
| Short Label | hTMCO4 |
| Category | organism-gene |
DAG ViewQ5TGY1 (TMCO4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C8 | Methylation | score1 | IEDB | 31844290 | ||
| C46 | Methylation | score1 | IEDB | 31844290 | ||
| T114 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S122 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S242 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T252 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y254 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K529 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S552 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C8 | Y8 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| T114 | M114 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S122 | C122 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S552 | L552 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] |
