iPTMnet Report for Q5TFE4 (NT5DC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5TFE4 / NT5D1_HUMAN
Protein Name 5'-nucleotidase domain-containing protein 1
Gene Name Name: NT5DC1
Synonyms:NT5C2L1;ORFNames:LP2642;
Organism Homo sapiens (Human)

PRO ID PR:Q5TFE4
DAG View
PRO Name 5'-nucleotidase domain-containing protein 1 (human)
Definition A 5'-nucleotidase domain-containing protein 1 that is encoded in the genome of human.
Short Label hNT5DC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5TFE4 (NT5DC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K171 Acetylation PhosphoSitePlus   UniProt 19608861
K187 Ubiquitination PhosphoSitePlus
C197 Methylation IEDB 31844290
T301 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K359 Acetylation PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
K455 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 F6 Biomuta DOID:1612 / breast cancer [ cosmic ]
K77 T77 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S113 W113 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S113 L113 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C197 F197 Biomuta DOID:3571 / liver cancer [ cosmic ]