iPTMnet Report for Q5TDH0 (DDI2)
Protein Information
| UniProt AC / UniProt ID | Q5TDH0 / DDI2_HUMAN |
| Protein Name | Protein DDI1 homolog 2 |
| Gene Name | Name: DDI2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q5TDH0 |
| PRO Name | protein DDI1 homolog 2 (human) |
| Definition | A protein DDI1 homolog 2 that is encoded in the genome of human. |
| Short Label | hDDI2 |
| Category | organism-gene |
DAG ViewQ5TDH0 (DDI2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T104 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S106 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332, ... | ||
| R108 | Methylation | score1 | PhosphoSitePlus | |||
| T115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S120 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S121 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S128 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332 | ||
| S150 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R182 | Methylation | score1 | PhosphoSitePlus | |||
| S194 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 17081983, ... | ||
| K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K283 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K337 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K338 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K389 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K398 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T104 | Phosphorylation | score0 | HPRD | 19664995, 20068231 | ||
| S105 | Phosphorylation | score0 | HPRD | 20230923 | ||
| S106 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 19664995, ... | ||
| T115 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S118 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S120 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S121 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S128 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S150 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S194 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K77 | M77 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| R108 | Q108 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S118 | A118 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S120 | L120 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S128 | A128 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| K170 | T170 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K289 | T289 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K289 | N289 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |
