iPTMnet Report for Q5TCQ9 (MAGI3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5TCQ9 / MAGI3_HUMAN
Protein Name Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
Gene Name Name: MAGI3
Synonyms:KIAA1634;
Organism Homo sapiens (Human)

PRO ID PR:Q5TCQ9
DAG View
PRO Name membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (human)
Definition A membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 that is encoded in the genome of human.
Short Label hMAGI3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5TCQ9 (MAGI3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T102 Phosphorylation PhosphoSitePlus
Y116 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
K378 Acetylation PhosphoSitePlus
K394 Acetylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus   UniProt 23186163
S659 Phosphorylation PhosphoSitePlus
S676 Phosphorylation PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y850 Phosphorylation PhosphoSitePlus
S953 Phosphorylation PhosphoSitePlus
S991 Phosphorylation PhosphoSitePlus
S1034 Phosphorylation PhosphoSitePlus
S1221 Phosphorylation PhosphoSitePlus
S1223 Phosphorylation PhosphoSitePlus
S1255 Phosphorylation PhosphoSitePlus
S1257 Phosphorylation PhosphoSitePlus
S1259 Phosphorylation PhosphoSitePlus
K1299 Ubiquitination PhosphoSitePlus
K1364 Methylation PhosphoSitePlus
K1387 Methylation PhosphoSitePlus
S1407 Phosphorylation PhosphoSitePlus
K1437 Acetylation PhosphoSitePlus
S1450 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y353 Phosphorylation PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
S595 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S225 F225 Biomuta DOID:4159 / skin cancer [ cosmic ]
S225 Y225 Biomuta DOID:363 / uterine cancer [ icgc ]
S261 F261 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
Y353 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S699 F699 Biomuta DOID:4159 / skin cancer [ cosmic ]
S832 F832 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1034 T1034 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1221 L1221 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ cosmic ]
S1450 Y1450 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]