iPTMnet Report for Q5TAQ9 (DCAF8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5TAQ9 / DCAF8_HUMAN
Protein Name DDB1- and CUL4-associated factor 8
Gene Name Name: DCAF8
Synonyms:H326,WDR42A;
Organism Homo sapiens (Human)

PRO ID PR:Q5TAQ9
DAG View
PRO Name DDB1- and CUL4-associated factor 8 (human)
Definition A DDB1- and CUL4-associated factor 8 that is encoded in the genome of human.
Short Label hDCAF8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5TAQ9 (DCAF8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
S99 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S129 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S130 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
T144 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
Y171 Phosphorylation PhosphoSitePlus
C174 Methylation IEDB 31844290
R204 Methylation UniProt 23455924
K236 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
C272 S-Nitrosylation dbSNO 26338901
C273 S-Nitrosylation dbSNO 26338901
K274 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
C392 Methylation IEDB 31844290
K438 Ubiquitination PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S99 Phosphorylation HPRD 18491316, 17081983, 19651622, ...18669648, 20166139, 20068231
S129 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S130 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S142 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S47 N47 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S99 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S129 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S142 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S142 L142 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S145 P145 Biomuta DOID:4159 / skin cancer [ cosmic ]
R204 H204 Biomuta DOID:10534 / stomach cancer [ cosmic ]
C273 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K374 Q374 Biomuta DOID:1324 / lung cancer [ cosmic ]