iPTMnet Report for Q5TAP6 (UTP14C)
Protein Information
| UniProt AC / UniProt ID | Q5TAP6 / UT14C_HUMAN |
| Protein Name | U3 small nucleolar RNA-associated protein 14 homolog C |
| Gene Name | Name: UTP14C Synonyms:KIAA0266; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q5TAP6 |
| PRO Name | U3 small nucleolar RNA-associated protein 14 homolog C (human) |
| Definition | A U3 small nucleolar RNA-associated protein 14 homolog C that is encoded in the genome of human. |
| Short Label | hUTP14C |
| Category | organism-gene |
Q5TAP6 (UTP14C) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S28 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330 | ||
| S36 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330 | ||
| S71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S80 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S97 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| S98 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T101 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T199 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T204 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K297 | Methylation | score1 | PhosphoSitePlus | |||
| K303 | Acetylation | score1 | PhosphoSitePlus | |||
| K306 | Methylation | score1 | PhosphoSitePlus | |||
| K308 | Methylation | score1 | PhosphoSitePlus | |||
| K313 | Sumoylation | score1 | PhosphoSitePlus | |||
| S450 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S456 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T508 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S536 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T539 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| K619 | Sumoylation | score1 | PhosphoSitePlus | |||
| K639 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S641 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K651 | Methylation | score1 | PhosphoSitePlus | |||
| T700 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y738 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S740 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S742 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S744 | Phosphorylation | score0 | HPRD | 20068231 | ||
| K762 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S36 | N36 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
| T101 | A101 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
| T101 | P101 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K284 | Q284 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K313 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K313 | R313 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S456 | F456 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y738 | * | Biomuta | DOID:1319 / brain cancer [ cosmic ] DOID:2174 / ocular cancer [ cosmic ] | |
| S742 | L742 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
DAG View