iPTMnet Report for Q5TA45 (INTS11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5TA45 / INT11_HUMAN
Protein Name Integrator complex subunit 11
Gene Name Name: INTS11
Synonyms:CPSF3L,RC68;
Organism Homo sapiens (Human)

PRO ID PR:Q5TA45
DAG View
PRO Name integrator complex subunit 11 (human)
Definition An integrator complex subunit 11 that is encoded in the genome of human.
Short Label hINTS11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5TA45 (INTS11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C74 Methylation IEDB 31844290
K115 Sumoylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
C195 Methylation IEDB 31844290
Y206 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K381 Sumoylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
C435 Methylation IEDB 31844290
K462 Sumoylation PhosphoSitePlus
K475 Sumoylation PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
C513 Methylation IEDB 31844290
K535 Ubiquitination PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
K593 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T482 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K127 E127 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K224 R224 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y266 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K500 T500 Biomuta DOID:363 / uterine cancer [ icgc ]
K593 R593 Biomuta DOID:3571 / liver cancer [ cosmic ]