iPTMnet Report for Q5T9L3 (WLS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T9L3 / WLS_HUMAN
Protein Name Protein wntless homolog
Gene Name Name: WLS
Synonyms:C1orf139,GPR177;ORFNames:UNQ85/PRO18667;
Organism Homo sapiens (Human)

PRO ID PR:Q5T9L3
DAG View
PRO Name protein wntless homolog (human)
Definition A protein wntless homolog that is encoded in the genome of human.
Short Label hWLS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T9L3 (WLS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K61 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T11 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K510 Ubiquitination PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K73 E73 Biomuta DOID:363 / uterine cancer [ icgc ]
K410 E410 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S413 N413 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S530 L530 Biomuta DOID:9256 / colorectal cancer [ cosmic ]