iPTMnet Report for Q5T848 (GPR158)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T848 / MGLYR_HUMAN
Protein Name Metabotropic glycine receptor precursor
Gene Name Name: GPR158
Synonyms:KIAA1136;
Organism Homo sapiens (Human)

PRO ID PR:Q5T848
DAG View
PRO Name probable G-protein coupled receptor 158 (human)
Definition A probable G-protein coupled receptor 158 that is encoded in the genome of human.
Short Label hGPR158
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T848 (GPR158) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S55 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
Y612 Phosphorylation PhosphoSitePlus
K732 Methylation PhosphoSitePlus
S753 Phosphorylation PhosphoSitePlus
K774 Ubiquitination PhosphoSitePlus   UniProt 18655026
T870 Phosphorylation PhosphoSitePlus
S872 Phosphorylation PhosphoSitePlus
S879 Phosphorylation PhosphoSitePlus
T913 Phosphorylation PhosphoSitePlus
T929 Phosphorylation PhosphoSitePlus
S931 Phosphorylation PhosphoSitePlus
S1193 Phosphorylation PhosphoSitePlus
S1194 Phosphorylation PhosphoSitePlus
S1197 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S55 L55 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S57 C57 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S57 F57 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S64 F64 Biomuta DOID:4159 / skin cancer [ cosmic ]
S142 N142 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K774 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T870 R870 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S872 L872 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S879 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S879 P879 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S931 F931 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S931 P931 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1193 F1193 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1194 Y1194 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1194 F1194 Biomuta DOID:4159 / skin cancer [ cosmic ]