iPTMnet Report for Q5T7P8 (SYT6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T7P8 / SYT6_HUMAN
Protein Name Synaptotagmin-6
Gene Name Name: SYT6
Organism Homo sapiens (Human)

PRO ID PR:Q5T7P8
DAG View
PRO Name synaptotagmin-6 (human)
Definition A synaptotagmin-6 that is encoded in the genome of human.
Short Label hSYT6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T7P8 (SYT6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S148 Phosphorylation PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
T164 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus   UniProt 21406692
S224 Phosphorylation PhosphoSitePlus
T227 Phosphorylation PhosphoSitePlus
T283 Phosphorylation P05771 (PRKCB) PhosphoSitePlus   Signor 16111671
T417 Phosphorylation P05771-2 (PRKCB) PhosphoSitePlus   Signor 16111671
T418 Phosphorylation P05771 (PRKCB) PhosphoSitePlus   Signor 16111671
K504 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S148 L148 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]
S216 L216 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S224 C224 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T227 A227 Biomuta DOID:10534 / stomach cancer [ cosmic ]