iPTMnet Report for Q5T6F0 (DCAF12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T6F0 / DCA12_HUMAN
Protein Name DDB1- and CUL4-associated factor 12
Gene Name Name: DCAF12
Synonyms:KIAA1892;
Organism Homo sapiens (Human)

PRO ID PR:Q5T6F0
DAG View
PRO Name DDB1- and CUL4-associated factor 12 (human)
Definition A DDB1- and CUL4-associated factor 12 that is encoded in the genome of human.
Short Label hDCAF12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T6F0 (DCAF12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S20 Phosphorylation PhosphoSitePlus
S32 Phosphorylation HPRD   PhosphoSitePlus 17081983
K35 Ubiquitination PhosphoSitePlus
S77 Phosphorylation HPRD   PhosphoSitePlus 18491316
K80 Ubiquitination PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
Y275 Phosphorylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S15 L15 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S271 F271 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y275 C275 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K398 I398 Biomuta DOID:1324 / lung cancer [ cosmic ]