iPTMnet Report for Q5T5X7 (BEND3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T5X7 / BEND3_HUMAN
Protein Name BEN domain-containing protein 3
Gene Name Name: BEND3
Synonyms:KIAA1553;
Organism Homo sapiens (Human)

PRO ID PR:Q5T5X7
DAG View
PRO Name BEN domain-containing protein 3 (human)
Definition A BEN domain-containing protein 3 that is encoded in the genome of human.
Short Label hBEND3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T5X7 (BEND3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation PhosphoSitePlus
S16 Phosphorylation HPRD 20068231
K20 Sumoylation PhosphoSitePlus
T23 Phosphorylation HPRD 20068231
S33 Phosphorylation HPRD   PhosphoSitePlus 20068231
S36 Phosphorylation HPRD   PhosphoSitePlus 20068231
T38 Phosphorylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
S54 Phosphorylation HPRD   PhosphoSitePlus 20068231
S55 Phosphorylation HPRD   PhosphoSitePlus 20068231
K56 Ubiquitination PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
S68 Phosphorylation HPRD   PhosphoSitePlus 20068231
K73 Ubiquitination PhosphoSitePlus
S92 Phosphorylation HPRD 20068231
S93 Phosphorylation PhosphoSitePlus
R104 Methylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
K129 Sumoylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
Y132 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K137 Acetylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
S164 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 19007248, 20068231
K176 Ubiquitination PhosphoSitePlus
T186 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S215 Phosphorylation HPRD   PhosphoSitePlus 20068231
S221 Phosphorylation HPRD   PhosphoSitePlus 20068231
S225 Phosphorylation HPRD   PhosphoSitePlus 20068231
S232 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
S379 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 19664994, 20068231
S383 Phosphorylation HPRD   PhosphoSitePlus 18452278
T385 Phosphorylation HPRD   PhosphoSitePlus 18452278
S388 Phosphorylation HPRD   PhosphoSitePlus 18452278
K427 Sumoylation PhosphoSitePlus
S489 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 19664994, ...18452278, 18669648, 20068231
S501 Phosphorylation HPRD 18452278
S503 Phosphorylation HPRD 18452278
S516 Phosphorylation PhosphoSitePlus
K528 Sumoylation PhosphoSitePlus
Y617 Phosphorylation HPRD 18767875
Y622 Phosphorylation HPRD 18767875
C643 Methylation IEDB 31844290
Y654 Phosphorylation PhosphoSitePlus
K700 Ubiquitination PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T7 I7 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S36 F36 Biomuta DOID:4159 / skin cancer [ cosmic ]
K129 R129 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S135 L135 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S146 L146 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
K158 T158 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S348 N348 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S503 I503 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S503 G503 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
C643 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S710 L710 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]