iPTMnet Report for Q5T5D7 (ZNF684)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T5D7 / ZN684_HUMAN
Protein Name Zinc finger protein 684
Gene Name Name: ZNF684
Organism Homo sapiens (Human)

PRO ID PR:Q5T5D7
DAG View
PRO Name zinc finger protein 684 (human)
Definition A zinc finger protein 684 that is encoded in the genome of human.
Short Label hZNF684
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T5D7 (ZNF684) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T52 O-Glycosylation GlyGen 30379171
K96 Ubiquitination PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
K134 Acetylation PhosphoSitePlus
K138 Acetylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
C248 Methylation IEDB 31844290
Y282 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
Y287 Phosphorylation PhosphoSitePlus
T322 Phosphorylation PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T52 A52 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
Y133 C133 Biomuta DOID:3571 / liver cancer [ cosmic ]
S284 L284 Biomuta DOID:4159 / skin cancer [ cosmic ]
T322 I322 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y327 C327 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]