iPTMnet Report for Q5T5C0 (STXBP5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T5C0 / STXB5_HUMAN
Protein Name Syntaxin-binding protein 5
Gene Name Name: STXBP5
Synonyms:LLGL3;
Organism Homo sapiens (Human)

PRO ID PR:Q5T5C0
DAG View
PRO Name syntaxin-binding protein 5 (human)
Definition A syntaxin-binding protein 5 that is encoded in the genome of human.
Short Label hSTXBP5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T5C0 (STXBP5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T76 Phosphorylation PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
Y502 Phosphorylation PhosphoSitePlus
T556 Phosphorylation PhosphoSitePlus
T668 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus   UniProt 23186163
S700 Phosphorylation PhosphoSitePlus
T703 Phosphorylation PhosphoSitePlus
T714 Phosphorylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus
S759 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 18088087, ...24275569
T762 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S774 Phosphorylation PhosphoSitePlus
S776 Phosphorylation PhosphoSitePlus
S778 Phosphorylation PhosphoSitePlus
S780 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S781 Phosphorylation PhosphoSitePlus
S782 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T784 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S785 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S900 Phosphorylation PhosphoSitePlus
S902 Phosphorylation PhosphoSitePlus
S906 Phosphorylation PhosphoSitePlus
Y914 Phosphorylation PhosphoSitePlus
T1039 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1058 Phosphorylation PhosphoSitePlus
S1076 Phosphorylation PhosphoSitePlus
S1131 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1142 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S202 Phosphorylation HPRD 18452278
Y234 Phosphorylation HPRD 20068231
S242 Phosphorylation HPRD 20068231
T556 Phosphorylation HPRD 20058876
Y657 Phosphorylation HPRD 20068231
T668 Phosphorylation HPRD 20068231
Y672 Phosphorylation HPRD 20068231
Y678 Phosphorylation HPRD 20068231
S712 Phosphorylation PhosphoSitePlus
S723 Phosphorylation HPRD 19413330, 18088087, 20058876, ...19651622, 18669648, 18707149, 20166139, 20068231
T726 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S742 Phosphorylation HPRD 19651622
S744 Phosphorylation HPRD   PhosphoSitePlus 18669648
S745 Phosphorylation HPRD   PhosphoSitePlus 19651622
S746 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648
T748 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648
S749 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648, 18212344


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S242 C242 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S242 F242 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y502 C502 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
Y672 C672 Biomuta DOID:3571 / liver cancer [ cosmic ]
S723 N723 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S745 L745 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S759 N759 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S781 L781 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S902 F902 Biomuta DOID:10534 / stomach cancer [ cosmic ]