iPTMnet Report for Q5T3J3 (LRIF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T3J3 / LRIF1_HUMAN
Protein Name Ligand-dependent nuclear receptor-interacting factor 1
Gene Name Name: LRIF1
Synonyms:C1orf103;
Organism Homo sapiens (Human)

PRO ID PR:Q5T3J3
DAG View
PRO Name ligand-dependent nuclear receptor-interacting factor 1 (human)
Definition A ligand-dependent nuclear receptor-interacting factor 1 that is encoded in the genome of human.
Short Label hLRIF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T3J3 (LRIF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K11 Sumoylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
S51 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...29351928, 30059200, 35254053, 35132862, 31492838, 35289036, 30620550
S52 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...29351928, 30059200, 35254053, 35132862, 31492838, 35289036, 30620550
S61 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...29351928, 30059200, 35254053, 35132862, 31492838, 35289036, 30620550
S65 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...29351928, 30059200, 35254053, 35132862, 31492838, 35289036, 30620550
T72 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...29351928, 30059200, 35254053, 35132862, 31492838, 35289036, 30620550
S85 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...29351928, 30059200, 35254053, 35132862, 31492838, 35289036, 30620550
T89 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...29351928, 30059200, 35254053, 35132862, 31492838, 35289036, 30620550
S90 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...29351928, 30059200, 35254053, 35132862, 31492838, 35289036, 30620550
S122 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
T167 O-Glycosylation GlyGen 23301498, 33214551, 34019948, ...29351928, 32938750, 30059200, 30620550, 35132862, 31492838, 35289036, 35254053
K175 Ubiquitination PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
S216 O-Glycosylation GlyGen 32938750
S218 O-Glycosylation GlyGen 32938750
K244 Sumoylation PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K259 Sumoylation PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K270 Sumoylation PhosphoSitePlus
K279 Methylation PhosphoSitePlus
K279 Sumoylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K290 Acetylation PhosphoSitePlus
K290 Sumoylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K308 Sumoylation PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
K316 Sumoylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K319 Sumoylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K325 Methylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K353 Sumoylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K370 Sumoylation PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
S402 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T405 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
K418 Sumoylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
K427 Sumoylation PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus   UniProt 23186163
S436 Phosphorylation PhosphoSitePlus   UniProt 23186163
K446 Ubiquitination PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
K467 Methylation PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
K470 Ubiquitination PhosphoSitePlus
K491 Sumoylation PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
T493 Phosphorylation PhosphoSitePlus
K500 Sumoylation PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus   UniProt 23186163
S506 Phosphorylation PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
K565 Sumoylation PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
S599 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S601 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K605 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
Y697 Phosphorylation PhosphoSitePlus
Y698 Phosphorylation PhosphoSitePlus
K702 Sumoylation PhosphoSitePlus
K702 Ubiquitination PhosphoSitePlus
K705 Ubiquitination PhosphoSitePlus
Y714 Phosphorylation PhosphoSitePlus
K722 Ubiquitination PhosphoSitePlus
T732 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K744 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S402 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231
S554 Phosphorylation HPRD 20068231
S558 Phosphorylation HPRD 20068231
S599 Phosphorylation HPRD 18669648
S601 Phosphorylation HPRD 18669648
T732 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation HPRD 20068231
S22 Phosphorylation HPRD 20068231
S63 Phosphorylation HPRD 18669648
S65 Phosphorylation HPRD 18669648
T196 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K50 M50 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S51 Y51 Biomuta DOID:363 / uterine cancer [ icgc ]
S61 Y61 Biomuta DOID:363 / uterine cancer [ icgc ]
S63 P63 Biomuta DOID:1324 / lung cancer [ cosmic ]
S63 F63 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T89 R89 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S122 Y122 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S122 F122 Biomuta DOID:4159 / skin cancer [ cosmic ]
T196 I196 Biomuta DOID:4159 / skin cancer [ cosmic ]
T214 A214 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K244 N244 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K308 E308 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K308 R308 Biomuta DOID:4159 / skin cancer [ cosmic ]
K325 R325 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T405 A405 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S408 F408 Biomuta DOID:4159 / skin cancer [ cosmic ]
S430 F430 Biomuta DOID:4159 / skin cancer [ cosmic ]
K449 R449 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K467 Q467 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K500 R500 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K509 Q509 Biomuta DOID:4159 / skin cancer [ cosmic ]
S599 F599 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S599 P599 Biomuta DOID:1324 / lung cancer [ cosmic ]
K605 N605 Biomuta DOID:1319 / brain cancer [ icgc ]
T732 I732 Biomuta DOID:4159 / skin cancer [ cosmic ]