iPTMnet Report for Q5T3F8 (TMEM63B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5T3F8 / CSCL2_HUMAN
Protein Name CSC1-like protein 2
Gene Name Name: TMEM63B
Synonyms:C6orf110;
Organism Homo sapiens (Human)

PRO ID PR:Q5T3F8
DAG View
PRO Name CSC1-like protein 2 (human)
Definition A CSC1-like protein 2 that is encoded in the genome of human.
Short Label hTMEM63B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5T3F8 (TMEM63B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y93 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
T110 Phosphorylation PhosphoSitePlus
S111 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S113 Phosphorylation PhosphoSitePlus
S114 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S115 Phosphorylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
Y297 Phosphorylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
Y347 Phosphorylation PhosphoSitePlus
K548 Acetylation PhosphoSitePlus
C691 Methylation IEDB 31844290
T746 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y93 Phosphorylation HPRD 19901323
Y106 Phosphorylation HPRD 19901323
S111 Phosphorylation HPRD 18578522, 18669648
S114 Phosphorylation HPRD 18767875, 18578522, 18669648
S115 Phosphorylation HPRD 18578522


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S96 L96 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y297 C297 Biomuta DOID:9256 / colorectal cancer [ cosmic ]